非增殖期糖尿病视网膜病变两种分期方法一致性的研究

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Abstract ObjectiveTo observe the consistency of the two staging method of non proliferative diabetic retinopathy.MethodsA retrospective study was performed on 162 eyes of 84 patients with non proliferative diabetic retinopathy who were examined by FFA in our hospital from January 2014 to June 2016.The fundus photograph of each eye in each patient and FFA images was confucted staging according to six classification method in our county and international classification method respectively.The consistency of the two methods in each period was examined.ResultsAmong 162 eyes,according to the six classification method,nonmydriaticfundus photograph was taken as the standard,DR with phase Ⅰdiagnosed were 59 eyes,phaseⅡdiagnosed were 37 eyes,and phaseⅢdiagnosed were 66 eyes.50°of fundus photograph was taken as the standard,DR with phaseⅠdiagnosed were 52 eyes,phaseⅡdiagnosed were 38 eyes,and phase Ⅲdiagnosed were 72 eyes.According to the international stage method,mild NPDR,moderate NPDR and severe NPDR patients was 34 eyes,30 eyes and 92 eyes respectively and 6 eyes were in PDR patients.The consistency of fundus photograph under hitomi and 50°of two fundus photographs under mydriasis judging the clinical staging of DR was better (Kappa=0.91).The consistency of six classification method and international classification method was general(Kappa= 0.634).Mild NPDR was seen as the screening threshold,the sensitivity and specificity for lesion at stage 1 was 100.0% and 85.9%respectively,and middle NPDR was seen as the screening threshold,the sensitivity and specificity for lesion at stageⅡ was 66.6%and 86.3%respectively,and severe NPDR was seen as the screening threshold,the sensitivity and specificity for lesion at stageⅢ was 71.0%and 91.4%respectively.ConclusionThe international staging under the guidance of FFA is more able to reflect the microvascular pathological changes and severity of diabetic retinopathy. Early FFA examination should be performed for patients at phaseⅠ,ⅡandⅢdiabetic retinopathy with diffuse hemorrhages and hemangioma.

Key words： Non proliferative phase Diabetic retinopathy Staging

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	Articles by authors
	FAN Li-min
	YANG Bo
	JI Qing
	LI Nai-yang

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FAN Li-min,YANG Bo,JI Qing, et al. Study on the consistency of two staging method of non proliferative diabetic retinopathy[J]. 中国当代医药, 2017, 24(13): 115-117.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I13/115

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