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| Study on the correlation between high risk factors of colon cancer and colonic lesions in Nanchang area |
| LIU Xiao-hui |
| Department of Gastroenterology,Nanchang Traditional Chinese and Western Medicine Hospital,Nanchang 330003,China |
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Abstract ObjectiveTo investigate the incidence rate of precancerous lesions for colon cancer in high-risk population of colon cancer through the colonoscopy screening the population having high-risk factors of colon cancer in Nanchang area to provide the basis for the early diagnosis and treatment of colon cancer.Methods158 cases having the high-risk factors of colon cancer and meeting the inclusion criteria were selected from 1128 healthy volunteers enrolled in the various community of Nanchang City from January 2012 to January 2016.158 cases were given the electron colonoscopy and pathology examination.The high risk rate of high-risk factors (family history of colon cancer and tumor,long-term drinking,history of polyps,chronic constipation,chronic diarrhea,bloody mucus,mental illness,disease of appendix,positive fecal occult blood)for high risk population of different age groups and the rate of colonoscopy,the detection rate of polyps and the number of severe atypical hyperplasia,and the correlation between high risk factors and severe atypical hyperplasia were counted.ResultsThe highest risk rate of high risk population in different age groups was 50-59 and 60-69 years old,and it was accounting for 17.94%and 18.35%respectively.The lowest in the 20-29 age group (7.69%).The proportion of high-risk factors,colonoscopy proportion was the highest in bloody mucus and fecal occult blood positive, and it was accounting for 29.11%and 30.38%,93.47%and 100.00%respectively.The detection rate of polyps was the highest in appendix disease,fecal occult blood positive,and it was both accounting for 66.67%.The correlation between high risk factors and severe atypical hyperplasia showed that there was a positive correlation between the incidence of family history of colorectal cancer,intestinal polyps,mucus bloody stool,fecal occult blood and severe atypical hyperplasia (P＜0.05).ConclusionThe detection rate of severe atypical hyperplasia in high-risk groups with visceral bloody stool and fecal occult blood is the highest,they are important risk factor of colon cancer,which plays a positive role in the early prevention of colorectal cancer.
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