海博刀行内镜黏膜下剥离术治疗消化道黏膜下病变的效果

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Abstract ObjectiveTo investigate the effect of Hybrid knife for endoscopic submucosal dissection in the treatment of gastrointestinal submucosal lesions.Methods80 hospitalized patients with gastrointestinal submucosal lesions treated in pur hospital from December 2015 to March 2017 were selected and they were randomly divided into Hybrid knife group (n=40)and control group(using conventional IT knife or Dual knife,n=40).The patients were all examined not have cardiopulmonary dysfunction,coagulation dysfunction and surgical contraindications.Operation index,curative effect and complications of two groups were observed.ResultsThe hospitalization time was(9.42±3.44)d in Hybrid knife group,and it was significantly shorter than that in control group[(12.00±4.36)]d(P＜0.05).Operative time was[(65.56±31.99)min] in HybridKnife group,and it was significantly shorter than that in control group[(104.37±42.38)min](P＜0.01).The size of the lesion between two groups had no significant difference(P＞0.05).The incidence rate of complications of abdominal pain(12.50%),perforation(2.50%)and it was shorter than that of control group(32.50%,15.00%)(P＜0.05).There was no statistical difference of the incidence rate of delayed hemorrhage between two groups(P＞0.05).The overall incidence rate of complications in the Hybrid knife group was 20.00%,which was significantly lower than the control group(52.50%) (P＜0.05).There was no significant difference of curative effect between two groups(P＞0.05).ConclusionHybrid knife for endoscopic submucosal dissection in the treatment of gastrointestinal submucosal lesions has the advantages of good effect,short operation and hospitalization time,less complications,and is worthy of clinical promotion and application.

Key words： Hybrid knife Endoscopic submucosal dissection Gastrointestinal submucosal lesions

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	Articles by authors
	HUANG Zhong
	WEI Wei
	LI Zhi
	CHEN Xin-lian

Cite this article:

HUANG Zhong,WEI Wei,LI Zhi, et al. Effect of Hybrid knife for endoscopic submucosal dissection in the treatment of gastrointestinal submucosal lesions[J]. 中国当代医药, 2017, 24(13): 20-22.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I13/20

[1]	Gotoda T，Kondo H，Ono H，et al.A new endoscopic mucosal resection procedure using an insulation-tipped electrosurgical knife for rectal flat lesious：report of two cases[J].Gastrointest Endosc，1999，50（4）：560-563.
[2]	FukamiN，Ryn CB，Said S，et al.Prospective，randomized study of conventional versus Hybridknife endoscopic submucosal dissection methods for the esophagus：an animal study[J].Gastrointest Endosc，2011，73（6）：1246-1253.
[3]	Japanese Gastric Cancer Association.Japanese gastric cancer treatment guidelines 2010（ver.3）[J].Gastric Cancer，2011，14 （2）：113-123.
[4]	Kakushima N，Fujishiro M.Endoscopic submucasal dissection for gastrointestinal neoplasms[J].World J Gastroenterol，2008，14（19）：2962-2967.
[5]	Neuhaus H，Wirths K，Schenk M，et al.Randomized controlled study of EMR versus endoscopic submucosal dissection with a water jet hybrid knife of esophageal lesions in a porcine inodel[J].Gastrointest Endosc，2009，7（1）：112-120.
[6]	Onozato Y，Ishihara H，Iizuka H，et al.Endoscopic submucosal dissection for early gastric cancers and large flat adenomas[J].Endoscopy，2006，38（10）：980-986.
[7]	傅承宏，薛寒冰，李晓波，等.内镜黏膜下剥离术治疗胃固有基层肿瘤的疗效和安全性[J].中华消化内镜杂志，2012，29（7）：385-388.
[8]	Oda I，Saito D，Tada M，et al.A multicenter retrospective study of endoscopic resection for early gastric cancer[J]. Gastric Cancer，2006，9（4）：262-270.
[9]	Cho KB，Jeon WJ，Kimm JJ.Worldwide experiences of endoscopic submucosal dissection：not just Eastern acrobaties[J]. Word J Gastroenterol，2011，17（21）：2611-2617.
[10]	Hammad H，Kaltenbach T，Soetikno R.Endoscopic submucosal Dissection for malignant esophageal lesions[J].Curr Gastroenterol Rep，2014，16（5）：386.
[11]	滕晓丽，陈洁.内镜黏膜下剥离术在早期食管癌及癌前病变中的疗效观察[J].临床消化病杂志，2016，28（4）：243.
[12]	FuJishiro M.Endoscopic submucosal dissection for stomach neoplasms[J].World J Gastroenterol，2006，12（32）：5108-5112.
[13]	刘莹，卢雪峰，王亚楠，等.内镜经黏膜下隧道肿瘤切除术治疗上消化道黏膜下肿瘤的探讨[J].中华消化杂志，2014，34（5）：334-336.
[14]	Tano S，Horiki N，Omata F，et al.Secnd and third-look endoscopy for the prevention of post-ESD bleeding[J].Medicine （Baltimore），2015，94（6）：e491.
[15]	Choi CW，Kim HW，Kang DH，et al.Clinical outcomes of second-look endoscopy after gastric endoscopic submucosal dissection：predictive factors with high risks of bleeding[J].Surg Endosc，2014，28（7）：2213-2220.