聊城市370例过敏性疾病患者血清过敏原特异性免疫球蛋白E 检测及流行病学特征分析

Abstract
Figure/Table
References (22)
Related Citation (15)

Download: PDF (493 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective The detection results of serum specific immunoglobulin E(sIgE)in patients with allergic diseases and the characteristics of allergens were analyzed.Methods Serum sIgE of 370 patients with allergic diseases admitted to Department of Anaphylaxis in Materal and Child Health Care Hospital of Dongchangfu County from April to June 2022 and July to September 2022 was detected,and the characteristics and allergens of the cases were analyzed.Results The sIgE positive rates of dust mite,wheat flour,house dust mite,pineapple and strawberry were 70.00%,65.14%,62.43%,45.68%and 44.32% respectively.There were 227 patients with allergic diseases in spring and 143 in autumn.Wheat flour,house dust mite,house dust mite,pineapple and strawberry were common allergens in spring,while dust mite,house dust mite,egg,humulus scandens and wheat flour were common allergens in autumn.Except mugwormwood,sycamore,birch,peach,apple,mango,cashew and cypress,the immunoglobulin E(IgE)positive rates of other 17 allergens were higher in spring than in autumn,and the differences were statistically significant (P＜0.05).The top 5 inhaled allergens in spring and autumn were dust mites,house dust mites,humulus scandens,common ragweed,willow (spring)and mugwormwood (autumn).The top 5 food allergens in spring were wheat flour,pineapple,strawberry,egg and soybean.The top 5 food allergens in autumn were egg,wheat flour,pineapple,milk and strawberry,and the positive rate of serum sIgE in spring was higher than that in autumn,the differences were statistically significant (P＜0.05).There were no significant differences in the types and incidence of major allergens between different genders(P＞0.05).Conclusion Dust mite,wheat flour,house dust mite,pineapple and strawberry were the main allergens in patients with sIgE positive allergic diseases.Dust mite was the main inhalation allergen,wheat flour and egg were the main food allergens.The positive rate of sIgE was different in different seasons.The results of this study provide certain reference for the prevention and treatment of allergic diseases in this area.

Key words： Allergic disease Serum immunoglobulin E Allergen Season Age

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2024/V31/I13/97

[1]	Charles FSI，Jenny MM.Allergic Rhinitis in Children and Adolescents[J].Immunol Allergy Clin North Am，2021，41（4）：613-625.
[2]	Nappi E，Paoletti G，Malvezzi L，et al.Comorbid allergic rhinitis and asthma：important clinical considerations[J].Expert Rev Clin Immunol，2022，18（7）：747-758.
[3]	Haahtela T，von Hertzen L，Makela M，et al.Finnish Allergy Programme 2008-2018-time to act and change the course[J].Allergy，2008，63（6）：634-645.
[4]	Gennaro DA，Carolina V，Antonio M，et al.Asthma-related deaths[J].Multidiscip Respir Med，2016，11（37）：1-5.
[5]	Cardona V，Ansotegui IJ，Ebisawa M，et al.World allergy organization anaphylaxis guidance 2020[J].World Allergy Organ J，2020，13（10）：100472.
[6]	Wise SK，Damask C，Roland LT，et al.International consensus statement on allergy and rhinology：Allergic rhinitis-2023[J].Int Forum Allergy Rhinol，2023，13（4）：293-859.
[7]	Agache I，Eguiluz-Gracia I，Cojanu C，et al.Advances and highlights in asthma in 2021[J].Allergy，2021，76（11）：3390-3407.
[8]	Turner PJ，Gowland MH，Sharma V，et al.Increase in anaphylaxis-related hospitalizations but no increase in fatalities：an analysis of United Kingdom national anaphylaxis data，1992-2012[J].J Allergy Clin Immunol，2015，135（4）：956-963.
[9]	王柳蕴，张敏.过敏性疾病的中医证型研究进展[J].光明中医，2021，36（22）：3919-3922.
[10]	黎军，李芳，刘书楠，等.社区及区县妇幼保健院过敏性疾病防治重庆共识[J].重庆医学，2022，51（24）：4141-4148，4154.
[11]	Zhang Y，Zhang L.Prevalence of allergic rhinitis in China[J].Allergy Asthma Immunol Res，2014，6（2）：105-113.
[12]	张雅琴，沈国松.婴幼儿尘螨严重过敏症的遗传学初步研究[J].中国卫生检验杂志，2023，33（10）：1223-1225，1254.
[13]	Demoly P，Liu AH，Rodriguea Del Rio P.A Pragmatic Primary Practice Approach to Using Specific IgE in Allergy Testing in Asthma Diagnosis，Management，and Referral[J].J Asthma Allergy，2022，16（15）：1069-1080.
[14]	Xu-De Z，Bei-Bei G，Xi-Juan W，et al.Serum IgE Predicts Difference of Population and Allergens in Allergic Diseases：Data from Weifang City，China[J].Mediators Inflamm，2021，25：6627087.
[15]	Khan DA.Allergic rhinitis and asthma：epidemiology and common pathophysiology[J].Allergy Asthma Proc，2014，35（5）：357-361.
[16]	刘玲，黄颖璇，谭改玲.顺德龙江地区0～6 岁食物过敏患者的过敏原检测与影响因素探讨[J].中国医药科学，2022，12（11）：179-182，186.
[17]	孟凡超，赵宗玲，刘晶晶，等.1878例过敏性疾病成年患者血清过敏原特异性IgE 检测及流行病学特征分析[J].华南预防医学，2021，47（12）：1536-1539，1544.
[18]	Sun X，Zhao J，Wang Q，et al.Prevalence of allergen sensitization among 15，534 patients with suspected allergic diseases in Henan Province，China[J].Asian Pac J Allergy Immunol，2019，37（2）：57-64.
[19]	周晓铃.儿童过敏性疾病181例过敏原检测分析[J].中国医药科学，2022，12（17）：115-118.
[20]	马婷婷，王洪田，陈艳蕾，等.北京地区门诊患者常见吸入过敏原致敏谱[J].中华临床免疫和变态反应杂志，2021，15（2）：136-143.
[21]	杨宇溪，邓耀波，苪黎，等.418例儿童过敏性疾病血清过敏原检测分析[J].云南医药，2023，44（5）：43-46.
[22]	Chen YL，Wang XY，Wang HT，et al.Analysis of airborne allergens in chronic urticaria with airway allergic diseases[J].Zhonghua Yu Fang Yi Xue Za Zhi，2021，55（8）：1011-1015.