内消瘰疬丸联合西药治疗空洞型非结核分枝杆菌肺病的效果观察

Abstract
Figure/Table
References (20)
Related Citation (15)

Download: PDF (480 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the effect of Neixiao Luoli Pills combined with western medicine in the treatment of cavitary nontuberculous mycobacterium (NTM) lung disease,and to provide a new therapeutic idea for clinical treatment.Methods Sixty-three patients with cavitary NTM lung disease admitted to Chest Hospital of Jiangxi Province from July 2020 to April 2023 were retrospectively analyzed,and divided into western medicine group (35 cases) and combined group (28 cases) according to treatment regimen.The western medicine group was treated with basic treatment,and the combined group was treated with Neixiao Luoli Pills.The main clinical manifestations and the changes of lesion extent and cavity in chest CT signs were observed in the two groups after intervention for 3 months.Results The treatment effect of cough and hemoptysis in combination group was better than that in western medicine group,and the total effective rate was higher than that in Western medicine group,the difference was statistically significant (P＜0.05).There was no significant difference in the treatment effect and total effective rate of chest tightness between the two groups (P＞0.05).Among the chest CT signs,the absorption of lung lesions and closure of cavity lesions in the combined group were better than those in the western medicine group,and the differences were statistically significant (P＜0.05).Conclusion Neixiao Luoli Pills combined with western medicine in the treatment of NTM lung disease can accelerate the remission of clinical symptoms and shorten the course of disease.The results of chest CT provide data support for the curative effect,which is worthy of clinical promotion and application.

Key words： Cavitary non-tuberculous Mycobacteria Neixiao Luoli Pills Chest CT Integration of traditional Chinese and western medicine

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2024/V31/I13/67

[1]	Winthrop KL，Marras TK，Adjemian J，et al.Incidence and Prevalence of Nontuberculous Mycobacterial Lung Disease in a Large U.S.Managed Care Health Plan，2008-2015[J].Ann Am Thorac Soc，2020，17（2）：178-185.
[2]	Tzou CL，Dirac MA，Becker AL，et al.Association between Mycobacterium avium Complex Pulmonary Disease and Mycobacteria in Home Water and Soil [J].Ann Am Thorac Soc，2020，17（1）：57-62.
[3]	Lee MR，Chang LY，Ko JC，et al.Nontuberculous mycobacteriallungdiseaseepidemiologyinTaiwan：Asystematicreview[J].J Formos Med Assoc，2020，119（Suppl 1）：S4-S12.
[4]	Sharma SK，Upadhyay V.Non-tuberculous mycobacteria：a disease beyond TB and preparedness in India[J].Expert Rev Respir Med，2021，15（7）：949-958.
[5]	Boonjetsadaruhk W，Kaewprasert O，Nithichanon A，et al.High rate of reinfection and possible transmission of Mycobacterium avium complex in Northeast Thailand[J].One Health，2022，14：100374.
[6]	任坦坦，陆普选，邓国防，等.2020 WHO 全球结核报告：全球与中国关键数据分析[J].新发传染病电子杂志，2020，5（4）：280-284.
[7]	陈益华，丘桂桂，尹良胜.尹良胜治疗非结核分枝杆菌肺病经验[J].浙江中西医结合杂志，2022，32（7）：673-675.
[8]	唐神结.非结核分枝杆菌病诊断与治疗专家共识解读[J].中国医刊，2016，51（3）：21-24.
[9]	张红梅，胡艳，刘国辉，等.非结核分枝杆菌肺病的临床特点及中医证型分析[J].广西中医药，2020，43（6）：17-20.
[10]	林玲香，陈明峰，周瑛瑛，等.内消瘰疬丸治疗颈部淋巴结结核疗效的Meta 分析[J].浙江中西医结合杂志，2022，32（12）：1156-1161.
[11]	郑筱萸.中药新药临床研究指导原则（试行）[S].北京：中国医药科技出版社，2002：57-60.
[12]	陈步东，陈辉，杜艳妮，等.非结核分枝杆菌肺病影像诊断专家共识[J].中国研究型医院，2021，8（3）：1-6.
[13]	段鸿飞.及时掌握研究进展切实提高非结核分枝杆菌病治疗水平[J].中国防痨杂志，2023，45（4）：329-332.
[14]	丰银平，郭净，张尊敬.102例非结核分枝杆菌肺病菌种分布与中医证候相关性分析[J].浙江中医杂志，2023，58（10）：716-718.
[15]	谭振鹏.内消瘰疬丸辅治初治菌阳空洞型肺结核临床观察[J].实用中医药杂志，2023，39（3）：520-521.
[16]	吴浩宇.内消瘰疬丸联合短程化疗对耐多药肺结核患儿的疗效[J].中国民康医学，2021，33（12）：7-8，11.
[17]	刘凡林.支气管扩张反复咳痰、咯血的药物治疗[J].家庭医学（下半月），2022（5）：54-55.
[18]	陈智慧.内消瘰疬丸联合结核丸对老年慢性阻塞性肺疾病合并肺结核患者肺功能及免疫功能的影响[J].中国药物经济学，2022，17（11）：65-68.
[19]	王嘉图，赵丽，尹世淩，等.内消瘰疬丸对乳腺增生患者乳腺超声指标及生殖激素水平的影响[J].临床和实验医学杂志，2022，21（14）：1541-1545.
[20]	喻剑翔.内消瘰疬丸联合己酮可可碱治疗肺结节病的疗效观察[J].基层医学论坛，2020，24（25）：3663-3664.