|
|
Cause analysis and prevention strategies of postoperative anastomotic fistula in laparoscopic colorectal cancer |
CHEN Yuanjian |
Department of Gastroenterology Surgery,Liuzhou People's Hospital,Guangxi Zhuang Autonomous Region,Liuzhou 545006,China |
|
|
Abstract Objective To study and analyze the causes of anastomotic leakage after laparoscopic surgery for colorectal cancer,and explore corresponding preventive measures.Methods A total of 676 patients with colorectal cancer who underwent laparoscopic surgery at the Department of Gastroenterology Surgery,Liuzhou People's Hospital from January 2018 to December 2022 were selected as the study objects.They were divided into a study group (49 cases with anastomotic leakage)and a control group (627 cases without anastomotic leakage)based on whether they experienced anastomotic leakage after surgery.Retrospective analysis was conducted on the clinical data of two groups of cases,and logistic regression analysis was used to analyze the influencing factors of anastomotic fistula after laparoscopic surgery for colorectal cancer.Results The results of single factor analysis showed that there were significant differences between the study group and the control group in gender,age,body mass index,diabetes,preoperative serum albumin,and operation time(P<0.05).The results of multiple factor analysis suggest that males (β=0.335,OR=2.561,95%CI:1.489-3.082),age ≥60 years old (β=0.361,OR=2.457,95%CI: 1.193-3.107),body mass index ≥24.9 kg/m2 (β=0.329,OR=2.379,95%CI:1.140-3.278),combined with diabetes(β=0.328,OR=2.369,95%CI: 1.207-3.114),preoperative serum albumin<35 g/L (β=0.357,OR=2.418,95%CI:1.245-3.098),surgery time ≥3.5 hours(β=0.348,OR=2.406,95%CI:1.352-3.069)were the risk factors for anastomotic fistula after laparoscopic colorectal cancer surgery (P<0.05).Conclusion Patients with colorectal cancer after laparoscopic surgery are affected by gender,age,body mass index,diabetes and other factors,and are prone to anastomotic leakage.
|
|
|
|
|
[1] |
韩轮,马艳飞.腹腔镜手术对结直肠癌患者氧化应激指标、疼痛因子及肿瘤标志物的影响[J].癌症进展,2023,21(1):93-96.
|
[2] |
司红军,闫齐森,李纲,等.腹腔镜手术与开腹手术治疗结直肠癌的临床效果评价[J].中国现代普通外科进展,2023,26(9):725-726,744.
|
[3] |
卢鑫,赵文召,黄鹏翀.腹腔镜结直肠癌根治术治疗肥胖结直肠癌患者的效果及对胃肠激素、机体循环功能的影响[J].检验医学与临床,2023,20(19):2872-2875.
|
[4] |
石彬,甄洪铖,花京文,等.腹腔镜下结直肠癌根治术对结直肠癌患者的影响[J].中外医疗,2023,42(14):71-75.
|
[5] |
赵建辉,孙东方,余乐.腹腔镜手术对结直肠癌患者免疫功能及预后的影响[J].癌症进展,2023,21(7):746-749.
|
[6] |
娄冬冬,蔡凌威.腹腔镜结直肠癌根治术对患者术后血清指标的影响[J].浙江创伤外科,2023,28(2):275-278.
|
[7] |
李柱,廖信芳,吕海钠,等.血清CRP、腹腔引流液CRP 在预测腹腔镜结直肠癌术后吻合口瘘的临床价值[J].广州医科大学学报,2021,49(3):77-82.
|
[8] |
中国结直肠癌诊疗规范(2020 年版)专家组.国家卫生健康委员会中国结直肠癌诊疗规范(2020 年版)[J].中华胃肠外科杂志,2020,23(6):521-540.
|
[9] |
郑民华,马君俊.2018 版《腹腔镜结直肠癌根治手术操作指南》更新要点[J].中华外科杂志,2019,57(3):224-226.
|
[10] |
周全博,杨帅玺,崔雯铭,等.机器人手术系统(或腹腔镜)联合结肠镜在T1 期结直肠癌手术中的应用:13例报告[J].中华胃肠外科杂志,2023,26(8):763-767.
|
[11] |
张宏林,荣万水,王延召.无气腹单孔腹腔镜结直肠癌根治术对结直肠癌患者应激反应及并发症的影响[J].癌症进展,2023,21(8):874-876,921.
|
[12] |
丁春明,沈长兵,周涛.腹腔镜结直肠癌根治术对老年结直肠癌患者手术指标及胃肠功能状态影响研究[J].系统医学,2023,8(16):118-121.
|
[13] |
唐燕辉.腹腔镜根治术对老年结直肠癌患者胃肠功能的影响[J].中外医疗,2023,42(8):49-53.
|
[14] |
李传江.腹腔镜辅助根治手术对结直肠癌患者免疫功能及术后并发症的影响[J].反射疗法与康复医学,2023,4(3):141-144.
|
[15] |
梁含理.侧方入路与中间入路腹腔镜结直肠癌根治术治疗结直肠癌的疗效对比[J].当代医学,2022,28(17):122-125.
|
[16] |
毛晓红,张永杰,苗华.血清MMP-9、PCT 水平与结直肠癌患者腹腔镜根治术后吻合口瘘的关系研究[J].浙江创伤外科,2022,27(2):209-212.
|
[17] |
晁祥嵩,王强,陈秉魁.血清清蛋白联合磷水平预测腹腔镜结直肠癌术后吻合口瘘的临床价值[J].医学理论与实践,2022,35(20):3540-3543.
|
[18] |
寇克剑,许军.结直肠癌术后吻合口瘘影响因素及早期预测指标[J].中国现代普通外科进展,2019,22(3):248-252.
|
[19] |
张国伟.腹腔镜结直肠癌根治术后患者发生吻合口瘘的危险因素分析[J].中国民康医学,2021,33(8):101-103.
|
[20] |
王雁军,王青兵,张勇,等.腹腔镜辅助直肠癌前切除术后吻合口瘘危险因素分析[J].山东医药,2015(33):74-75.
|
[21] |
曾庆智,黄启奎,邓杰建.结直肠癌患者术后吻合口瘘发生的危险因素分析[J].中国临床新医学,2019,12(11):1236-1239.
|
[22] |
刘渊,柯友忠,贾后军.脂质代谢指标预测结直肠癌合并糖尿病患者术后吻合口瘘的临床研究[J].现代医药卫生,2023,39(18):3093-3096.
|
[23] |
周晓华,徐豪,徐光齐,等.腹腔镜直肠癌根治术后发生吻合口瘘的现状及其相关影响因素探讨[J].现代医学与健康研究(电子版),2022,6(3):112-114.
|
[24] |
李亚萍,寇志坚,阎文军.结直肠癌围手术期低蛋白血症的研究进展[J].中国医学创新,2023,20(7):182-188.
|
[25] |
李伟,刘立刚,杨俊泉,等.经肛门拖出标本的全腹腔镜结直肠癌根治术(NOSES Ⅳ式)术后吻合口瘘发生的危险因素分析[J].中国癌症防治杂志,2023,15(5):564-569.
|
[26] |
王旭强,温红旭.L-LAR 术后吻合口瘘发生诱导因素分析[J].医学理论与实践,2023,36(17):2942-2944.
|
[27] |
万源,徐峰,杜俊东.结直肠癌术后吻合口瘘的危险因素及预防的研究进展[J].现代消化及介入诊疗,2023,28(9):1179-1184.
|
|
|
|