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| Application and research progress of microneedle in dermatology |
| LI Yanhong1 LI Zhenjie2 |
1.Department of Traditional Chinese Medicine,Guangzhou Dermatology Hospital,Guangdong Province,Guangzhou 510095,China;
2.Department of Zhongshan Fourth Road Outpatient,Guangzhou Dermatology Hospital,Guangdong Province,Guangzhou 510095,China |
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Abstract Microneedling is an emerging therapeutic method in recent years.In recent years,its clinical application has been gradually promoted and popularized,especially in dermatology.Microneedles have been widely used in pigmentary skin diseases,alopecia,acne,scars,facial rejuvenation and other fields,with a very broad application prospect.Microneedling can form a large number of small micro-channels on the surface of the skin,so that the drug can easily penetrate the stratum corneum of the skin,thereby increasing the transdermal absorption of the drug and making the drug play a better effect.Microneedle combined with Tacrolimus in the treatment of vitiligo,enhance curative effect,speed up the curative effect in time;Microneedle combined with Minoxidil can improve the curative effect of various alopecia diseases.Compared with laser and autologous platelet rich plasma(PRP),microneedle is easier to carry out and cheaper to treat scars.Microneedles can also be used in the treatment of herpes zoster neuralgia,neurodermatitis,eczema,rosacea,hormone-dependent dermatitis and other skin diseases.In particular,the development of soluble microneedles provides a new safe and effective way for microneedles to treat diseases.
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