Objective To analyze the demographic data,clinical characteristics,clinical types and time trends of hospitalized patients with single-center aortic dissection in ten years.Methods The relevant data of 651 patients diagnosed with major arterial dissection in the General Hospital of Ningxia Medical University from January 2011 to December 2020 were retrospectively collected,including socio-demographic data,clinical symptoms,comorbidities,pathogenesis,family genetic history,treatment methods and hospitalization outcomes,etc.The influencing factors of death in Stanford type A and Stanford type B patients were analyzed.Results In the past 10 years,the number of hospitalized patients with aortic dissection showed A gradual upward trend,and Stanford type A patients accounted for 39.63%and Stanford type B patients accounted for 60.37%,with a male-to-female ratio of 3.62∶1 and an average age of (52.88±11.46)years.14.75%of the patients reported definite inducement,mainly physical activity and external impact,10.91%of the patients reported definite family genetic history.In terms of clinical symptoms,96.31%of the patients had obvious pain,among which the chest,back and abdomen were the highest (66.97%,62.83% and 32.26%).There was statistical significance in clinical outcomes of different types of aortic dissection patients in conservative treatment(P＜0.05).Multivariate logistic regression analysis showed that early emergency surgery was A protective factor for the prevention of death in Stanford Type A aortic dissection patients,and drinking was a risk factor for hospital death (P＜0.05).Control of systolic blood pressure within the appropriate range was a protective factor for in-hospital death in Stanford type B aortic dissection patients,and length of stay and conservative treatment were risk factors for in-hospital death (P＜0.05).Conclusion Early emergency surgery is A protective factor for preventing death in Stanford type A aortic dissection patients,and controlled contraction is a protective factor for in-hospital death in Stanford type B aortic dissection patients.Therefore,identifying the risk factors for death of aortic dissection can provide a reference for clinical diagnosis and treatment.