肺部感染儿童支气管肺泡灌洗液病原及细胞学分析

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Abstract Objective To analyze the pathogenic and cytological components of bronchoalveolar lavage fluid (BALF) in children with pulmonary infection and to provide evidence for clinical diagnosis and treatment. Methods A total of 42 children hospitalized in Quanzhou Children's Hospital from August 2021 to October 2022 were selected as the research objects. Among them, 23 children diagnosed with bacterial pneumonia by BALF culture were in the bacterial pneumonia group, and 19 children without bacterial growth cultured by BALF after foreign body removal were in the bronchial foreign body group. The pathological analysis of BALF in the two groups was carried out by cytological sedimentation method. Results The main bacterial pneumonia in 23 cases was Streptococcus pneumoniae infection, lung CT was easy to be complicated with atelectasis. The most common bronchial foreign bodies in 19 cases were in the left main bronchus, and nut foreign bodies were the main ones. The percentage of neutrophil and C-reactive protein (CRP) in bacterial pneumonia group were higher than those in bronchial foreign body group, and the differences were statistically significant (P＞0.05). The percentage of lymphocyte in bacterial pneumonia group was lower than that in bronchial foreign body group, the difference was statistically significant (P＞0.05). The percentage of neutrophils in BALF in bacterial pneumonia group was higher than that in bronchial foreign body group, and the difference was statistically significant (P＜0.05). There were no significant differences in the percentage of lymphocytes, macrophages and ciliary columnar epithelial cells in BALF between the two groups (P＞0.05). Conclusion Streptococcus pneumoniae is the most common bacterial pneumonia in children, and the cytological composition of BALF is mainly neutrophils, which provides a basis for clinical diagnosis and treatment, and avoids clinical antibiotic abuse.

Key words： Bacterial pneumonia Bronchoalveolar lavage fluid Cytological analysis Child

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	YOU Yuting ZENG Li′e LIN Chunyan CHEN Qionghua LIN Jieru ZHENG Jinyang

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YOU Yuting ZENG Li′e LIN Chunyan CHEN Qionghua LIN Jieru ZHENG Jinyang. Etiology and cytological analysis of bronchoalveolar lavage fluid in children with pulmonary infection[J]. 中国当代医药, 2024, 31(1): 64-67.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2024/V31/I1/64

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