慢性乙型肝炎合并抑郁症的影响因素分析

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Abstract Objective To investigate the influencing factors of chronic hepatitis B combined with depression.Methods A population of chronic hepatitis B patients who admitted to the Department of Infectious Disease of Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine from January 2022 to January 2023 were selected as the research subjects.By using a questionnaire survey,general information such as age,gender,weight,marital status,smoking and drinking history,education status,as well as traditional Chinese medicine constitution analysis,traditional Chinese medicine syndrome analysis and depression score were collected.Use logistic regression to analyze the influencing factors of chronic hepatitis B complicated with depression.Results A total of 365 patients were ultimately included in the study,including 96 patients with depression and 299 patients without depression.The results of univariate analysis showed that there were statistically significant differences in the comparison of depression among different types of traditional Chinese medicine constitution,traditional Chinese medicine syndrome differentiation and family history of depression(P＜0.05).The results of multivariate logistic regression analysis showed that Qi stagnation(OR=5.579,95%CI:2.063-15.087),blood stasis(OR=5.590,95%CI: 2.09-15.553),liver depression and spleen deficiency (OR=4.875,95%CI: 1.696-14.013),liver depression and phlegm obstruction (OR=6.515,95%CI:2.343-18.119),liver stagnation and Qi stagnation (OR=4.282,95%CI: 1.555-11.791)and family history of depression(OR=18.847,95%CI:5.416-65.584)were independent risk factors for chronic hepatitis B complicated with depression (P＜0.05).Conclusion Family history of depression,Qi stagnation,blood stasis,liver stagnation and spleen deficiency,liver stagnation and phlegm obstruction,liver stagnation and Qi stagnation are independent risk factors for chronic hepatitis B complicated with depression.It is necessary to pay attention to these high-risk factors in clinical practice and provide certain reference value for clinical intervention.

Key words： Chronic hepatitis B Depression Traditional Chinese medicine constitution Influencing factors

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[1]	尤红，王福生，李太生，等.慢性乙型肝炎防治指南（2022年版）[J].传染病信息，2023，36（1）：1-17.
[2]	Wong MCS，Huang JLW，George J，et al.The changing epidemiology of liver diseases in the Asia-Pacific region[J].Nat Rev Gastroenterol Hepatol，2019，16（1）：57-73.
[3]	Freeland C，Racho R，Kamischke M，et al.Health-related quality of life for adults living with hepatitis B in the United States：a qualitative assessment[J].J Patient Rep Outcomes，2021，5（1）：121-129.
[4]	Tang LSY，Covert E，Wilson E，et al.Chronic Hepatitis B Infection：A Review[J].JAMA，2018，319（17）：1802-1813.
[5]	Monroe SM，Harkness KL.Major Depression and Its Recurrences：Life Course Matters[J].Annu Rev Clin Psychol，2022，18：329-357.
[6]	Kessler RC，Bromet EJ.The epidemiology of depression across cultures[J].Annu Rev Public Health，2013，34：119-138.
[7]	Huang Y，Wang Y，Wang H，et al.Prevalence of mental disorders in China：a cross-sectional epidemiological study[J].Lancet Psychiatry，2019，6（3）：211-224.
[8]	Vu TTM，Le TV，Dang AK，et al.Socioeconomic Vulnerability to Depressive Symptoms in Patients with Chronic Hepatitis B[J].Int J Environ Res Public Health，2019，16（2）：255.
[9]	Zung WW.A self-rating depression scale[J].Arch Gen Psychiatry，1965，12：63-70
[10]	徐春燕，田金洲，时晶，等.抑郁症的中医证候特征研究[J].中华中医药学刊，2013，31（4）：810-813.
[11]	中华中医药学会.中医体质分类与判定[J].中华养生保健，2009，9：38-39.
[12]	Choi KW，Kim YK，Jeon HJ.Comorbid Anxiety and Depression：Clinical and Conceptual Consideration and Transdiagnostic Treatment[J].Adv Exp Med Biol，2020，1191：219-235.
[13]	Swetlitz N.Depression's Problem With Men[J].AMA J Ethics，2021，23（7）：586-589.
[14]	益明辉（SITTHICHOCK VADPHIMAI）.中医与泰医体质学说比较及泰国2 型糖尿病中医体质分布的研究[D].长春：长春中医药大学，2022.
[15]	王琦.中医体质学[M].北京：人民卫生出版社，2009：9-15.
[16]	王琦.9 种基本中医体质类型的分类及其诊断表述依据[J].北京中医药大学学报，2005，28（4）：1-8.
[17]	蒋健.郁证诊疗新体系的构建[J].中华中医药杂志，2023，38（1）：18-25.
[18]	魏玮，荣培晶，陈建德，等.虚、滞、瘀、郁-现代慢性疾病中医病机新认知[J].中国中西医结合杂志，2020，40（10）：1264-1267.
[19]	赵曼，余国龙，杨天伦.某三甲综合医院心内科门诊患者焦虑抑郁症状及相关因素[J].中国临床心理学杂志，2012，20（2）：188-189，184.
[20]	梁健宁，顾雨婷，周晨，等.抑郁症患者外显及内隐情绪面孔的反应抑制特点[J].中国心理卫生杂志，2022，36（10）：817-823.
[21]	Ma L，Hu P，Zhang J，et al.Purpurin exerted antidepressant-like effects on behavior and stress axis reactivity：evidence of serotonergic engagement[J].Psychopharmacology（Berl），2020，237（3）：887-899.
[22]	Troubat R，Barone P，Leman S，et al.Neuroinflammation and depression：Areview[J].EurJNeurosci，2021，53（1）：151-171.
[23]	苏丽雅，戴红芳，张文玉，等.气郁体质与自主神经功能、焦虑/抑郁情绪的相关性研究[J].中华中医药学刊，2014，32（3）：553-555.
[24]	熊玲.气郁体质及其台北地区分布情况研究[D].北京：北京中医药大学，2007.