化学发光免疫分析在临床检验中的诊断价值

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Abstract

Objective To explore the diagnostic value of chemiluminescence immunoassay in clinical examination.Methods A total of 50 cases of patients with suspected hepatitis B admitted to Linyi Maternal and Child Health Hospital from May 2020 to April 2021 were selected as research objects.All of them were examined by chemiluminescent immunoassay and hepatitis B virus DNA load.The positive rates of serum markers,and hepatitis B virus DNA load and application values were analyzed.Clinical diagnosis was the gold standard.Results The positive rates of hepatitis B surface antigen(HBsAg),hepatitis B e antigen(HBeAg),hepatitis B e antibody(HBeAb)detected by chemiluminescent immunoassay were higher than those of hepatitis B virus DNA load,and the differences were statistically significant(P＜0.05).The sensitivity,accuracy and negative predictive value of chemiluminescent immunoassay were higher than those of hepatitis B virus DNA load,and the differences were statistically significant(P＜0.05).However,there were no statistically significant differences in specificity and positive predictive value between the two groups(P＞0.05).Conclusion The application value of chemiluminescence immunoassay is higher than that of hepatitis B virus DNA load,and the sensitivity,accuracy and positive predictive value are higher,which is worth popularizing.

Key words： Clinical test Hepatitis B virus DNA load testing Chemiluminescence immunoassay Serum markers Application value

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WEI Hongwei. Diagnostic value of chemiluminescence immunoassay in clinical examination[J]. 中国当代医药, 2022, 29(29): 149-151转156.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I29/149

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