Edible and medicinal fungi not only have a certain number of species,but also have unique nutrients and pharmacological effects,which have attracted more and more attention in academic research.There are many contents about the application of edible and medicinal fungi in the traditional Chinese medicine materia medica classics,including drug determination,quantity record,clinical application of traditional Chinese medicine and prescriptions,etc.At present,there have been edible and medicinal fungi as the main raw material or molecular source of drugs in clinical use,or are undergoing clinical trials,or have obtained official approval to make health food.It can be seen that edible and medicinal fungi have played an important role in clinical and health care,and have high application value to improve human health.Although the resources of the medicinal food bacteria is very rich,but now the use value of medicinal food bacteria discovered only a small part,should be through various efforts to turn their potential for practical application of broader,deeper,in nutrition,food science,TCM,clinical medicine,philology,opening up a new topic,advancing the medicinal food bacteria in clinical and health care function of related research.