加味通络方治疗气虚血瘀兼阴虚型急性脑梗死的效果

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Abstract Objective To investigate the effect of Jiawei Tongluo Recipe on patients with acute cerebral infarction of Qi deficiency and blood stasis combined with Yin deficiency,and the effect of Jiawei Tongluo Recipe on patients with mercaptopyruvate thiotransferase-3 (3-MST),vascular endothelial growth factor (VEGF),angiotensin Ⅱ(AngⅡ),National Institutes of Health Stroke scale (NIHSS) and transcranial Doppler (TCD) indicators.Methods A total of 100 patients with acute cerebral infarction of Qi deficiency and blood stasis combined with Yin deficiency admitted to Hongqi Hospital Affiliated to Mudanjiang Medical University from January to December 2021 were selected as the research objects.They were divided into observation group and control group by random number table method,with 50 cases in each group.The patients in the observation group were treated with Jiawei Tongluo Recipe,while the patients in the control group were treated with conventional Western medicine.The NIHSS scores,the levels of 3-MST,AngⅡand VEGF before and after treatment were compared between the two groups.The levels of TCD indexes before and after treatment were compared between the two groups.Results Before treatment,there were no significant differences in serum 3-MST levels between the two groups (P＞0.05).The serum 3-MST level of the observation group after treatment was higher than that of the control group,and the difference was statistically significant (P＜0.05).There were no significant differences in serum VEGF and AngⅡlevel between the two groups before treatment (P＞0.05).The serum VEGF level of the observation group after treatment was higher than that of the control group,the AngⅡlevel of the observation group after treatment was lower than that of the control group,and the difference was statistically significant (P＜0.05).There was no significant difference in NIHSS score between the two groups before treatment (P＞0.05).The NIHSS score of the observation group after treatment was lower than that of the control group,and the difference was statistically significant (P＜0.05).Before treatment,there were no significant differences in blood flow spectrum morphology (Vs),mean blood flow velocity (Vm) and pulsitility index (PI) between the two groups (P＞0.05).After treatment,the Vs and Vm levels of the observation group were lower than those of the control group,and PI of the observation group was higher than that of the control group,and the differences were statistically significant (P＜0.05).Conclusion Jiawei Tongluo Recipe has obvious effect on on patients with acute cerebral infarction of Qi deficiency and blood stasis combined with Yin deficiency.It can effectively regulate and establish cerebral collateral compensatory vessels and further control various serum levels.

Key words： Jiwei Tongluo Recipe Qi deficiency and blood stasis Yin deficiency type Acute cerebral infarction Effect analysis

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[1]	崔娜，佟佳馨，朱晓彤，等.通窍活血汤合星香散加减联合醒脑开窍针刺治疗急性脑梗死（痰瘀互结证）临床观察[J].中国中医急症，2022，31（1）：105-108.
[2]	李翠静，张雪.联用自拟的益气活血汤和醒脑开窍针法对脑梗死患者进行早期康复治疗的效果分析[J].当代医药论丛，2021，19（4）：137-138.
[3]	田芬.观察通脉消梗汤联合丁苯酞氯化钠注射液治疗脑梗死急性期的临床疗效及对炎性因子表达的影响[J].饮食保健，2021（11）：14.
[4]	刘斌.中国急性缺血性脑卒中诊治指南解读与急诊处理[C]//.2017 第13 届中国中西医结合学会灾害医学学术年会与第12 届广东省中西医结合学会灾害医学学术年会暨广东省中西医结合学会卫生应急学专业委员会成立大会暨2017 灾害医学与急危重症高端论坛中国中西医结合研究灾害医学十年回顾资料集.2017.
[5]	余小萍，方祝元.中医内科学[M].3 版.上海：上海科学技术出版社，2018，5：397.
[6]	李章晗，黎华茂，艾年年.半夏白术天麻汤联合丁苯酞注射液治疗急性脑梗死（风痰阻络证）疗效及对炎性因子、MCP、VEcadherin 的影响[J].中国中医急症，2021，30（7）：1272-1274.
[7]	朱兆武.急性脑梗死患者加味四妙勇安汤治疗的有效性及对患者血清超敏C 反应蛋白纤维蛋白原水平的影响[J].山西医药杂志，2021，50（6）：914-917.
[8]	姚青刚，陆锋，张梅，等.补阳还五汤加味联合氢溴酸樟柳碱治疗进展性脑梗死疗效及对血清D-二聚体、C 反应蛋白的影响[J].现代中西医结合杂志，2021，30（25）：2793-2796.
[9]	陈峰，吴曦，穆迎涛，等.血府逐瘀汤联合常规治疗对急性脑梗死患者炎症反应、氧化应激、内皮及相关因子的影响[J].海南医学院学报，2019，25（10）：762-765，770.
[10]	陈凤清，罗小燕.补阳还五汤联合rt-PA 静脉溶栓治疗急性脑梗死的效果及对炎症因子、脑动脉血流的影响[J].中外医学研究，2021，19（36）：18-22.
[11]	雷华斌，张恒.补阳还五汤加减治疗气虚血瘀型脑梗死的临床效果及对凝血-纤溶功能和miR-151a-3p、miR-210 表达的影响[J].临床医学研究与实践，2021，6（29）：141-143.
[12]	韩雪娟，马超，贾云朋，等.开窍醒神汤联合丁苯酞注射液治疗脑梗死急性期的临床疗效及其对NSE、炎性因子表达的影响[J].东方药膳，2021（21）：184.
[13]	杨立平.补阳还五汤加减辅助治疗急性脑梗死患者的疗效及对脑水肿和脑脊液中β2微球蛋白（β2-MG）水平的影响[J].中外女性健康研究，2021（9）：92-93.
[14]	何键林.针灸联合中药补阳还五汤治疗对脑梗死恢复期气虚血瘀型患者炎性因子及神经因子水平的影响[J].中医外治杂志，2021，30（3）：32-34.
[15]	王永军，石良静，范正超，等.益气养阴通络方对早期糖尿病肾病患者炎症因子及肾功能的影响[J].西部中医药，2020，33（5）：82-85.
[16]	梁春玲，陈晓杰，刘祖发，等.补阳还五汤联合西药治疗急性脑梗死疗效及对患者血管斑块稳定性及血清因子水平的影响[J].陕西中医，2020，41（9）：1200-1204.
[17]	武文娟，邵艳敏，尹小君.血清TNF-α、IL-6、CRP 水平对老年急性脑梗死患者介入治疗后睡眠障碍的预测价值[J].东南大学学报（医学版），2021，40（6）：760-765.
[18]	吴松，金肇权，孙丹，等.注射用鼠神经生长因子联合注射用重组人TNK 组织型纤溶酶原激活剂治疗急性脑梗死患者的临床研究[J].中国临床药理学杂志，2022，38（3）：199-202.
[19]	吴章松，陈然，徐菲，等.NLR、PLR、hs-CRP、Hb、D-D 与急性脑梗死非溶栓治疗后出血性转化的相关性分析[J].临床和实验医学杂志，2021，20（1）：22-25.
[20]	刘玉，张建，郭涛，等.抗菌药物降阶梯疗法联合支气管肺泡灌洗术治疗急性脑梗死合并肺部感染患者的疗效及预后观察[J].贵州医药，2021，45（5）：775-776.