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| Effect of ultrafiltration combined with Injection of Yiqi Fumai in the treatment of refractory heart failure |
| WANG Jing1 PENG Bo1 WANG Haicun1 CUI Jing1 TAN Liye |
1.Department of Cardiology,the Second Affiliated Hospital of Mudanjiang Medical College,Heilongjiang Province,Mudanjiang 157011,China;
2.Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Mudanjiang Medical College,Heilongjiang Province,Mudanjiang 157011,China |
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Abstract Objective To analyze the effect of ultrafiltration combined with Injection of Yiqi Fumai in the treatment of refractory heart failure.Methods A total of 120 patients with refractory heart failure hospitalized in the Second Affiliated Hospital of Mudanjiang Medical College from June 2017 to May 2020 were selected as the research objects.According to the random number table method,they were divided into control group and study group,with 60 cases in each group.The control group was treated with Enalapril Tablets,Spironolactone Tablets and Metoprolol Succinate Sustained-Release Tablets,while the study group was treated with heart failure ultrafiltration combined with Injection of Yiqi Fumai.The 6-min walking distance,cardiac function improvement and treatment safety were compared between the two groups before and after treatment.Results After treatment,6 min walking distance of the two groups were longer than those before the treatment,left ventricular ejection fraction (LVEF),stroke volume (SV),cardiac output (CO)levels were higher than those before the treatment,and the 6 min walking distance of the study group was longer than that of the control group,LVEF,SV,CO levels were higher than those of the control group,the differences were statistically significant (P＜0.05).There were no significant differences in systolic blood pressure,heart rate,sodium ion concentration,potassium ion concentration,bicarbonate,hemoglobin,platelet count,serum creatinine and blood urea nitrogen levels between the two groups before and after treatment (P＞0.05).Conclusion Ultrafiltration combined with Injection of Yiqi Fumai has significant clinical effect and high safety in the treatment of refractory heart failure.
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