胰岛素强化干预在ICU急危重症患者中的应用效果

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Abstract Objective To investigate the application effect on the intensive insulin intervention on critically ill patients in Emergency ICU.Methods A total of 60 ICU critically ill patients with stress hyperglycemia admitted to ShangRao People's Hospital from January to December 2021 were selected as research objects.They were randomly divided into routine treatment group (target blood sugar controlled at 6.1-8.1 mmol/L) and intensive treatment group (target blood sugar controlled at 4.1-6.1 mmol/L),with 30 patients in each group.The routine treatment group was treated with conventional insulin treatment intervention,and the intensive treatment group was treated with insulin intensive therapy.The disease indicators,blood glucose management effect before and after treatment and prognosis were compared between the two groups.Results The ICU stay time,electrocardiogram monitoring time,insulin pumping time and discharge time in intensive treatment group were shorter than those in conventional treatment group,with statistically significant differences (P＜0.05).After treatment,the fasting plasma glucos (FPG) level of the two groups was lower than that before treatment,and the insulin sensitivity index (ISI) and insulin resistance index (HOMA-IR) levels were higher than those before treatment,with statistically significant differences (P＜0.05).After treatment,the FPG level in intensive treatment group was lower than that in conventional treatment group,and the ISI and HOMA-IR levels in intensive treatment group were higher than those in conventional treatment group,with statistically significant differences(P＜0.05).There was no statistically significant difference in the total incidence of poor prognosis such as hypoglycemia,dyspnea,nosocomial infection and death between the two groups (P＞0.05).Conclusion Intensive insulin intervention can improve stress hyperglycemia and prognosis of critically ill patients in ICU.

Key words： Insulin therapy Intensive care unit Stress hyperglycemia Insulin resistance

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I28/66

[1]	殷拥军，许勇，黄恺悦，等.入院应激性高血糖及糖化血红蛋白对非糖尿病急性心肌梗死患者PCI 术后的影响[J].西部医学，2018，30（1）：81-83.
[2]	李鹏飞，冷飞.达格列净治疗急性心肌梗死合并应激性高血糖的效果[J].中国当代医药，2020，27（20）：65-68.
[3]	叶圳，李炯，杨吉勇，等.自拟养阴活血益胃汤联合胰岛素强化治疗对非糖尿病胃癌根治术后应激性高血糖患者糖代谢、应激状态、能量代谢的影响[J].现代中西医结合杂志，2018，27（9）：913-917.
[4]	单米亚，陈潞楠.评估应激性高血糖对急性ST 段抬高心梗患者不良心血管事件发生和远期预后的影响[J].中国医院药学杂志，2019，39（18）：1860-1864.
[5]	胡亚楠，韩非.围术期液体管理与应激性高血糖的预防[J].临床麻醉学杂志，2020，36（1）：86-89.
[6]	解柳芸.利拉鲁肽对超重及肥胖2 型糖尿病患者体质指数和胰岛素抵抗的影响[J].医药前沿，2018，8（10）：47-48.
[7]	张坤源，廖长品，李廷阳.应激性高血糖与脑出血相关性的研究进展[J].重庆医学，2021，50（7）：1232-1237.
[8]	刘雪松，张新，杜卉莲，等.重症脑出血患者应激性高血糖短期胰岛素强化治疗的临床观察[J].中国医药指南，2018，16（1）：76.
[9]	姚志本.胰岛素静脉泵控制缺血性卒中急性期应激性高血糖与治疗预后关系研究[J].北方药学，2017，14（1）：28-29.
[10]	杭永青.ICU 内应激性高血糖患者胰岛素治疗及护理的研究进展[J].临床医药文献电子杂志，2019，6（34）：196-197.
[11]	林长亮，冯星火.强化胰岛素治疗对ICU 重症颅脑损伤和并应激性高血糖患者预后的影响[J].中国实用乡村医生杂志，2020，27（4）：70-72.
[12]	朱星星，张红，尚福泰，等.胰岛素强化治疗对重度颅脑损伤应激性高血糖患者HMGB1/NF-κB 通路的影响[J].中华危重病急救医学，2019，31（8）：949-952.
[13]	王金梅.短期胰岛素强化治疗联合参芪降糖颗粒对非糖尿病性脑梗死伴发应激性高血糖的调控效果及对促炎细胞因子的影响[J].现代中西医结合杂志，2019，28（19）：2115-2119.
[14]	吴敏，戎天艺，周慧，等.胰岛素强化治疗对脑出血后应激性高血糖患者血清神经元特异性烯醇化酶和S100β蛋白水平的影响[J].山西医药杂志，2021，50（6）：992-994.
[15]	李利华，刘龙清.急性脑卒中应激性高血糖的影响因素及其采用胰岛素强化治疗的效果分析[J].中国实用医药，2017，12（13）：106-107.