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| Application effect of Xiao′er Feireqing Granules in children with bronchopneumonia |
| XU Han1 ZHANG Fan2 ZHU Chunhui3▲ |
1. Department of Pediatrics, Jiangxi Children′s Hospital, Jiangxi Province, Nanchang 330000, China;
2. Department of Respiratory Medicine, Jiangxi Children′s Hospital, Jiangxi Province, Nanchang 330000, China;
3. Department of Infectious Disease, Jiangxi Children′s Hospital, Jiangxi Province, Nanchang 330000, China |
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Abstract Objective To investigate the application effect of Xiao′er Feireqing Granules in children with bronchopneumonia. Methods From October 2020 to December 2021, 84 children with bronchialpneumonia with phlegm and heat obstructing lung treated in Jiangxi Children′s Hospital were selected as the study subjects. They were divided into observation group (42 cases) and control group (42 cases) by random number table method. The control group was treated with conventional symptomatic basic treatment, and the observation group was treated with Xiao′er Feireqing Granules. The clinical efficacy, traditional Chinese medicine syndromes scores and the levels of white blood cells, neutrophils, monocytes and lymphocytes in peripheral blood were compared between the two groups, and the occurrence of adverse reactions were compared between the two groups. Results The total effective rate in the observation group was higher than that in the control group after 5 days of treatment, and the difference was statistically significant (P<0.05).After 5 days of treatment, the scores of traditional Chinese medicine syndromes in both groups were lower than those before treatment, and the differences were statistically significant (P<0.05). The score of throat phlegm/expectoration traditional Chinese medicine syndromes in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). After 5 days of treatment, the levels of white blood cells, neutrophils and monocytes in both groups were lower than those before treatment, and the differences were statistically significant (P<0.05). The level of neutrophils in observation group was higher than that in control group, and the difference was statistically significant (P<0.05). There were no adverse reactions in both groups during treatment. Conclusion The treatment of children with bronchopneumonia with Xiao′er Feireqing Granules can regulate the immune level of the body, improve the traditional Chinese medicine syndrome of the patients, improve the total effective rate of clinical treatment, and the safety during the treatment is good.
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