Objective To analyze the value of feedforward control theory in the management of laparoscopic surgical instruments. Methods A total of 40 patients who underwent laparoscopic surgery in the Second People′s Hospital of Yichun City between March 2019 and February 2020 were selected as the control group, and 40 patients who underwent laparoscopic surgery between March 2020 and February 2021 were selected as the observation group. The control group received routine management of laparoscopic surgical instruments, and the observation group received feedforward control management mode. The incidence of adverse instrument events, average time of taking instruments, loss of instruments, satisfaction with instrument management and medical care were compared between the two groups. Results The total incidence of adverse device events in the observation group was 5.00%, which was lower than 20.00% in the control group, and the difference was statistically significant (P＜0.05). The average time of instrument taking in the observation group was shorter than that in the control group, and the difference was statistically significant (P＜0.05). The total loss rate of the observation group was 2.50%, which was lower than that of the control group (25.00%), and the difference was statistically significant (P＜0.05). The satisfaction scores of each device management in the observation group were higher than those in the control group, and the differences were statistically significant (P＜0.05). The total satisfaction rate of doctors and nurses in the observation group was 96.67%, which was higher than 73.33% in the control group, and the difference was statistically significant (P＜0.05). Conclusion Applying feedforward control theory in the management of laparoscopic surgical instruments can effectively reduce the occurrence of adverse events and loss of instruments, shorten the time of taking instruments, and improve the effectiveness of instrument use as well as medical staff′s satisfaction.