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| Clinical value of platelet/lymphocyte ratio in left ventricular thrombosis after acute anterior wall myocardial infarction |
| LIU Zeyu1 FENG Yingjun1 LIU Xuanxuan |
1. Department of Physical Diagnostics, Yuebei People's Hospital, Guangdong Province, Shaoguan 512026, China;
2. Department of Cardiology, Yuebei People's Hospital, Guangdong Province, Shaoguan 512026, China |
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Abstract Objective To investigate the clinical value of platelet/lymphocyte ratio (PLR) in left ventricular thrombosis after acute anterior wall myocardial infarction. Methods A total of 131 patients with acute anterior myocardial infarction diagnosed with acute anterior myocardial infarction in Yuebei People's Hospital from January 2017 to July 2021 were retrospectively selected as research objects, according to the occurrence of left ventricular thrombus (LVT), they were divided into thrombosis group (n=32) and control group (n=99). Blood samples were drawn from the median cubital vein on admission for the determination of biochemical and coagulation parameters. LVT is diagnosed by echocardiography or contrast echocardiography. Results Univariate analysis showed that there were significant differences in the proportion of ventricular aneurysm, platelet count (PLT), neutrophil count (NEU), PLR, left ventricular ejection fraction (LVEF) in thrombosis group and control group (P＜0.05). Multivariate analysis showed that PLR (β=0.075, OR= 1.078, 95%CI=1.025-1.134), ventricular aneurysm formation (β=2.193, OR=8.960, 95%CI=1.252-64.111) were risk factors for LVT occurence. LVEF (β=-0.145, OR=0.865, 95%CI=0.784-0.953) was a protective factor for LVT occurrence (P＜0.05). Receiver operation characteristic (ROC) curve showed the best cut-off point of PLR for predicting LVT was 215.35, the area under curve (AUC) was 0.756 (95%CI=0.661-0.852, P＜0.001), the sensitivity was 0.563, and the specificity was 0.818. Conclusion In patients with anterior myocardial infarction, aneurysm formation and elevated PLR are independent risk factors for the occurrence of LVT, and elevated LVEF is a protective factor for the occurrence of LVT. PLR is related to the occurrence of LVT, it is a valuable indicator for judging LVT in clinical practice.
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