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| Clinical value of dynamic contrast-enhanced magnetic resonance imaging combined with diffusion weighted imaging in the diagnosis of uterine sarcoma |
| ZHOU Hua |
| Department of Radiology, Ganzhou Maternal and Child Health Hospital, Jiangxi Province, Ganzhou 341000, China |
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Abstract Objective To investigate the clinical value of dynamic enhanced magnetic resonance (DCE-MRI) combined with diffusion-weighted imaging (DWI-MRI) in the diagnosis of uterine sarcoma. Methods The clinical data of 26 patients with uterine sarcoma in Ganzhou Maternal and Child Health Hospital from June 2014 to December 2021 were retrospectively analyzed, and the clinical data of 29 patients with degenerative uterine fibroids in Ganzhou Maternal and Child Health Hospital during the same period were selected for analysis. All patients were diagnosed by conventional color ultrasound, DCE-MRI and DWI-MRI before surgery. The maximum contrast enhancement rate (MCER), apparent dispersion coefficient (ADC) and peak time (TTP) of patients with uterine sarcoma and degenerative uterine fibroids were compared, and the efficacy of conventional color ultrasound, DCE-MRI combined with DWI-MRI in the diagnosis of uterine sarcoma was analyzed using pathological examination as the gold standard. Results The MCER of patients with uterine sarcoma was higher than that of patients with degenerative uterine fibroids, TTP was shorter than that of patients with degenerative uterine fibroids, ADC was lower than that of patients with degenerative uterine fibroids, and the differences were statistically significant (P＜0.05). The coincidence rate, sensitivity and specificity of conventional color ultrasonography in the diagnosis of uterine sarcoma were 70.91% (39/55), 61.54% (16/26) and 79.31% (23/29), respectively. The coincidence rate, sensitivity and specificity of MRI (DCE combined with DWI) in the diagnosis of uterine sarcoma were 78.18% (43/55), 80.77% (21/26) and 75.86% (22/29), respectively. The receiver operating characteristic (ROC) curve showed that MRI (95%CI=0.845-0.926, AUC=0.911) in the diagnosis of uterine sarcoma was higher than conventional color ultrasound (95%CI=0.881-0.927, AUC=0.898). Conclusion DCE-MRI combined with DWI-MRI has good sensitivity and high coincidence rate in the diagnosis of uterine sarcoma, which can provide scientific reference for the preoperative non-invasive diagnosis of uterine sarcoma.
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