血清C反应蛋白、中性粒细胞与淋巴细胞比值与尿毒症腹膜透析患者发生感染性腹膜炎的相关性

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (442 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the correlation between serum C-reactive protein (CRP),neutrophil-to-lymphocyte ratio (NLR) and the occurrence of infectious peritonitis (SP) in uremic peritoneal dialysis (PD) patients.Methods A total of 196 patients with uremia received PD treatment in the Second Hospital of Longyan City from January 2018 to December 2020 were selected as the research objects,and they were divided into two groups according to whether they had SP or not,and 42 patients with SP were set as the observation group,154 patients without SP were set as the control group.The convenient sampling method was used.The serum CRP and NLR levels of the two groups were compared,and the correlation between the serum CRP and NLR levels and the occurrence of SP was analyzed,as well as the value of CRP and NLR in evaluating SP.Results The levels of serum CRP and NLR in the observation group were higher than those in the control group,and the difference was statistically significant (P＜0.05).Serum CRP and NLR levels were positively correlated with the occurrence of SP (P＜0.05).The area under curve (AUC) of CRP for the diagnosis of SP was 0.838 (95% confidence interval: 0.760-0.916),the sensitivity was 0.806,and the specificity was 0.833;the AUC of NLR for diagnosing SP was 0.867 (95% confidence interval: 0.786-0.948),the sensitivity was 0.871,and the specificity was 0.858.Conclusion Serum CRP and NLR levels are closely related to the occurrence of SP in uremic PD patients.

Key words： Uremia Infectious peritonitis Peritoneal dialysis C-reactive protein Neutrophil-to-lymphocyte ratio

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I22/103

[1]	张道法，苏淑娟.腹膜透析相关性腹膜炎易感因素分析[J].临床和实验医学杂志，2018，17（9）：999-1002.
[2]	马莹，王颖，王海云，等.腹膜透析相关性腹膜炎患者短期预后不良危险因素的分析[J].中国医学科学院学报，2018，40（1）：13-20.
[3]	刘栋，张碧莹，刘蕊.血清PCT，SOD 水平检测在腹膜透析相关性腹膜炎中的临床价值[J].现代检验医学杂志，2019，34（4）：116-119.
[4]	周飞燕，吴凌慧，汤素华，等.IL-6 和CRP 与PCT 检测早期诊断腹膜透析感染性腹膜炎及预后的临床价值[J].中华医院感染学杂志，2020，30（18）：2772-2775.
[5]	方味味，刘桂凌，李庆根，等.NLR 和PLR 在腹膜透析相关性感染中的诊断价值探讨[J].临床肾脏病杂志，2020，20（1）：12-18.
[6]	中国腹膜透析相关感染防治专家组.腹膜透析相关感染的防治指南[J].中华肾脏病杂志，2018，34（2）：139-148.
[7]	葛均波，徐永健.内科学[M].8 版.北京：人民卫生出版社，2013：459-462.
[8]	Musbahi A，Kanakala V.A modified laparoscopic peritoneal dialysis insertion technique，the′one scar technique′ can minimise short and long term complications：a retrospective cohort study[J].J Vasc Access，2021，22（5）：744-748.
[9]	As′habi A，Najafi I，Tabibi H，et al.Prevalence of sarcopenia and dynapenia and their determinants in iranian peritoneal dialysis patients[J].Iran J Kidney Dis，2018，12（1）：53-60.
[10]	黄庆龙，吴岳春，胡斌.单发与多发腹膜透析相关性腹膜炎的临床特点分析[J].中国现代医学杂志，2020，30（9）：110-114.
[11]	李军，陈文.腹膜透析患者血清超敏C 反应蛋白和营养指标检测结果分析[J].中国实验诊断学，2019，23（2）：264-265.
[12]	柳秀平，彭敏峰，吕凌云.白细胞计数、降钙素原和C-反应蛋白检测在日间非卧床腹膜透析相关性腹膜炎诊疗中的应用价值[J].中国卫生检验杂志，2020，30（6）：732-734.
[13]	许娟，刘小静，秦丽君.血浆PCT NLR 及MCP-1 指标检测对肝硬化合并细菌性腹膜炎患者的诊断及预后评估价值[J].河北医学，2020，26（8）：1300-1304.
[14]	吴岳春，黄庆龙，杨明榴，等.NLR 与MLR 对腹膜透析患者腹腔感染的诊断及预后评估价值[J].中华医院感染学杂志，2021，31（6）：852-856.
[15]	侯文娟，陶舒曼，方味味，等.腹膜透析患者基线血清中性粒细胞/淋巴细胞比值与首次腹膜炎的关联性[J].临床肾脏病杂志，2021，21（1）：33-37.