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Effect of Carboprost Tromethamine, Carboprost Methylate Suppository and Oxytocin in the treatment of postpartum hemorrhage |
WANG Jia |
Department of Obstetrics and Gynecology, Xingcheng Women and Children′s Hospital, Liaoning Province, Xingcheng 125100, China |
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Abstract Objective To study the clinical effects of Carboprost Tromethamine, Carboprost Methylate Suppository combined with Oxytocin in the treatment of postpartum hemorrhage. Methods A total of 56 patients suffering from postpartum hemorrhage admitted to our hospital from May 2017 to April 2019 were selected as the research subjects and divided into the observation group (n=28) and the control group (n=28) according to the random number table method. In the control group, conventional Oxytocin combined with Carboprost Methylate Suppository was used, and in the observation group, Carboprost Tromethamine was added on the basis of the control group. The bleeding volume before treatment, the bleeding volume at 2, 24 h after delivery, and the decrease in hemoglobin at 24 h were recorded.The overall response rate, the total incidence of adverse reactions and the changes of heart rate (HR), diastolic blood pressure (DBP), and systolic blood pressure (SBP) before and after treatment in the two groups were compared. Results The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). The bleeding volume of the observation group at 2 h and 24 h after delivery and the decrease of hemoglobin at 24 h after delivery were less than those of the control group, and the differences were statistically significant (P<0.05). After treatment, the HR, SBP, and DBP of the observation group were higher than those of the control group, with statistical significance (P<0.05). There was no statistical difference in the total incidence of adverse reactions between the two groups (P>0.05). Conclusion In the treatment of patients with postpartum hemorrhage,Carboprost Tromethamine, Carboprost Methylate Suppository combined with Oxytocin can remarkably reduce the amount of postpartum hemorrhage in puerpera and stabilize the patient′s vital signs such as HR and blood pressure.The curative effect is remarkable, the safety is good.
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Received: 20 February 2020
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