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Changes and significance of serum homocysteine and hypersensitive Creactive protein in patients with hypertension |
LI Ying ZENG Xiu-ping XIE Shu-ying |
Department of Clinical Laboratory,Shaoguan Institute of Occupational Disease Control |
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Abstract Objective To explore the changes and significance of serum homocysteine and high-sensitivity C-reactive protein in patients with hypertension.Methods A total of 100 patients with hypertension admitted to the Shaoguan Institute of Occupational Disease Control from February 1,2015 to February 10,2016 were selected as the observation group (according to their different degrees of disease,they were divided into mild [30 cases],moderate [30 cases] and severe [40 cases]).In addition,100 healthy subjects were selected as the control group.The levels of serum homocysteine and high-sensitivity C-reactive protein of subjects in two groups were measured,and the levels of subjects in the two groups were analyzed..Results Serum homocysteine and high-sensitivity C-reactive protein levels in the observation group were higher than those in the control group,the differences were statistically significant (P<0.05).Serum homocysteine and high-sensitivity C-reactive protein levels in severe patients were higher than those in mild and moderate patients,serum homocysteine and high-sensitivity C-reactive protein levels in moderate patients were higher than those in mild patients,the differences were statistically significant (P<0.05).Conclusion Serum homocysteine and high-sensitivity C-reactive protein are closely related to the development of hypertension,which can reflect the severity of hypertension,provide a favorable basis for the later treatment of hypertension,and is worthy of promotion and application in clinical.
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