加减瓜蒌薤白半夏汤联合西药治疗痰浊内阻型冠心病的效果及对心功能指标的影响

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Abstract Objective To explore the clinical effect of Modified Gualou Xiebai Banxia Decoction combined with Western medicine in the treatment of coronary heart disease with turbid phlegm and internal obstruction.Methods A total of 84 patients with turbid phlegm and internal obstruction coronary heart disease who were admitted to the Lichuan National Hospital of Traditional Chinese Medicine in Enshi Prefecture of Hubei Province from October 2018 to June 2020 were selected,and they were divided into the study group (42 cases) and the control group (42 cases) according to random number table method.The ontrol group was treated with Western medicine,while the study group was treated with Modified Gualou Xiebai Banxia Decoction on the basis of the control group.Both groups were treated continuously for 30 days.The clinical efficacy,traditional Chinese medicine syndrome scores before and after treatment,cardiac function indexes and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the study group was 95.24%,which was higher than 80.95% in the control group,and the difference was statistically significant (P＜0.05).The traditional Chinese medicine syndromes score of chest tightness,chest pain,shortness of breath,body weight,body fat and phlegm after treatment in the two groups were lower than those before treatment,and the traditional Chinese medicine syndromes score of chest tightness,chest pain,shortness of breath,body fatness and phlegm after treatment in the study group were lower than those in the control group,the differences were statistically significant (P＜0.05).The left ventricular end diastolic diameter (LVEDD) and left ventricular end systolic diameter(LVESD) after treatment in the two groups were lower than those before treatment,and the left ventricular ejection fraction (LVEF) after treatment in the two groups were higher than those before treatment,the differences were statistically significant (P＜0.05).After treatment,the levels of LVEDD and LVESD in the study group were lower than those in the control group,and the levels of LVEF in the study group was higher than that in the control group,the differences were statistically significant (P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion Modified Gualou Xiebai Banxia Decoction combined with Western medicine has achieved good results in the treatment of turbid phlegm and internal obstruction coronary heart disease.The clinical symptoms of the patients have been effectively improved,the level of cardiac function is improved,the side effects are few,the safety is high,and it is good for prognosis and worth popularizing.

Key words： Coronary heart disease Turbid phlegm and internal obstruction type Gualou Xiebai Banxia Decoction Aspirin Enteric-Coated Tablets Metoprolol Heart function

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	XIANG Li
	CHEN Qiu
	WANG Jianhua

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XIANG Li,CHEN Qiu,WANG Jianhua. Effect of Modified Gualou Xiebai Banxia Decoction combined with Western medicine in the treatment of coronary heart disease with turbid phlegm and internal obstruction and its influence on indexes of cardiac function[J]. 中国当代医药, 2022, 29(17): 154-157.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I17/154

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