黄芪不同炮制品对脾虚小鼠胃肠功能的影响与多糖含量的相关性分析

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Abstract ObjectiveTo investigate correlation of effects of different processed products of Astrsgalus membranaceus on gastrointestinal function of spleen deficiency mice and polysaccharides content.Methods60 healthy mice were selected and randomly divided into the control group,the model group,the Astragalus quality test group,the honey Astragalus test group,the rice Astragalus test group and the Astragalus membranaceus experimental group.There were 10 mice in each group.Determination of content of Astragalus Polysaccharides of different processed products of colorimetric method using phenol sulfuric acid,and the gastric emptying rate of carbon powder in small intestine of mice with spleen deficiency of Huangqi markers of different processed products of rhubarb lapactic advance rate and compare correlation between.ResultsDifferent processed products of spleen deficiency mice gastric emptying rate and intestinal propulsive rate:the influence of honey Astragalus Astragalus,astragalus,rice bran,astragalus.Compared with the model group,the different processed products of Astragalus had some inhibition on the rate of gastric emptying and the rate of small bowel propulsion.Compared with the Astragalus membranaceus,the Astragalus membranaceus prepared by the adjuvant inhibited the gastric emptying rate and the intestinal propulsive rate.The effects of different Astragalus processed products on gastric emptying rate and intestinal propulsive rate of spleen deficiency mice were different.Honey astragalus root>rice astragalus root>Astragalus membranaceus>Astragalus membranaceus.There was no significant difference in the gastric emptying rate and the small intestinal propulsive rate between the processed Astragalus and the control group,indicating that the gastrointestinal function was close to the normal level after treatment.ConclusionThe gastric emptying rate and intestinal propulsive rare of spleen deficiency mice controlled by different processed products of Astragalus membranaceus have positive correlation with polysaccharides content.

Key words： Astragalus membranaceus Drug Processing Spleen deficiency mice Gastrointestinal function Polysaccharides content Correlation

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	ZHAO Wei
	XIAN Xiao-min

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ZHAO Wei,XIAN Xiao-min. Correlation analysis of effects of different processed products of Astragalus membranaceus on gastrointestinal function of spleen deficiency mice and polysaccharides content[J]. 中国当代医药, 2017, 24(20): 145-147.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I20/145

[1]	仝欣.黄芪主要活性成分的药理作用[J].时珍国医国药，2011，22（5）：1246-1249.
[2]	吴发宝，陈希元.黄芪药理作用研究综述[J].中药材，2004，27（3）：232-234.
[3]	张蔷，高文远，满淑丽.黄芪中有效成分药理活性的研究进展[J].中国中药杂志，2012，37（21）：3203-3204.
[4]	姜琛璐，汤承，蹇宇，等.黄芪多糖免疫调节作用研究进展[J].食品科学，2013，11（34）：327-331.
[5]	李利明.不同炮制方法对黄芪化学成分的影响[J].中医中药科学，2014，14（17）：85-87.
[6]	张洪波，任春晓.黄芪叶提取及黄芪多糖测定方法研究[J].黑龙江医药，2005，18（1）：6-8.
[7]	陈玉霞，林峰，莫娟，等.两种黄芪多糖提取方法比较[J].试验室研究与探索，2015，34（3）：19-30.
[8]	罗燕，谷新利，惠文巧，等.黄芪多糖对脾虚小鼠消化吸收功能的影响[J].黑龙江畜牧兽，2009（9）：110-112.
[9]	祝婧，钟凌云，龚千锋，等.升麻不同炮制品对脾气虚动物胃肠功能的影响[J].中国试验方剂学杂志，2015，21（21）：1-4.
[10]	田洛，宜依，范荣军，等.酸碱提取法提取黄芪多糖[J].吉林大学学报，2006，44（4）：652-657.
[11]	傅紫琴，蔡宝昌，卞长霞.山药及其麸炒品德多糖成分对脾虚小鼠胃肠功能的影响[J].药学与临床研究，2008，16（3）：181-183.
[12]	吴永平，曹园，曹正中.黄芪活性成分最佳提取工艺探讨[J].时珍国医国药，2001，12（10）：876-877.
[13]	王汝俊，傅定中，王建华，等.补中益气汤对“脾虚”大鼠胃黏膜易损伤性的复健作用研究[J].广州中医学院学报，1995，12（3）：31-32.
[14]	周金黄，王建华.中药药理与临床研究进展[J].北京：军事医学科学出版社，1995：183.
[15]	黄立群.黄芪活性成分的药理活性研究进展[J].赤峰学院学报（自然版），2009，25（9）：119-120.