不同临床特征肝病患者肝移植术中输血量的比较

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Abstract Objective To compare the blood transfusion volume in patients with different clinical characteristics of liver diseases during liver transplantation. Methods The clinical data of 96 patients with liver transplantation admitted to Beijing Youan Hospital Affiliated to Capital Medical University from October 2018 to October 2019 were analyzed retrospectively. The intraoperative blood transfusion volume of patients with different sex, age, basic liver disease and operation methods were compared. The preoperative coagulation indexes in patients with different basic liver diseases was compared. Results There were no significant differences in suspended red blood cells, plasma and platelets transfused in patients of different sex and age (P>0.05). There were significant differences in prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT) and fibrinogen (Fib) of patients with different basic liver diseases before operation (P<0.05). The preoperative PT and APTT of patients with acute and chronic liver failure were longer than those of patients with primary liver cancer, hepatitis cirrhosis and other liver diseases, the preoperative TT of patients with acute and chronic liver failure was shorter than that of patients with primary liver cancer, hepatitis cirrhosis and other liver diseases, the preoperative Fib of patients with acute and chronic liver failure was lower than that of patients with primary liver cancer, hepatitis cirrhosis and other liver diseases, the differences were statistically significant (P<0.05). There were significant differences in suspended red blood cells and plasma transfusion in patients with different basic liver diseases (P<0.05). There was no significant difference in platelet transfusion between patients with different basic liver diseases (P>0.05). The suspended red blood cells and plasma transfusions in patients with acute and chronic liver failure were significantly higher than those in patients with primary liver cancer and hepatitis cirrhosis, the differences were statistically significant (P<0.05). The suspended red blood cells and plasma transfusions in patients with other liver diseases were greater than those in patients with primary liver cancer, the differences were statistically significant (P<0.05). There were no significant differences in the transfusion of suspended red blood cells, plasma and platelets in patients with different operation methods (P>0.05). Conclusion The blood demand of liver transplantation patients must be individualized by evaluating preoperative factors, reasonably grasping the indications of blood transfusion, ensuring adequate blood supply and reducing related complications.

Key words： Liver transplantation Component transfusion Coagulation function Liver diseases

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	YANG Gengxia
	HUANG Xiaojie

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YANG Gengxia,HUANG Xiaojie. Comparison of blood transfusion volume in patients with different clinical characteristics of liver diseases during liver transplantation[J]. 中国当代医药, 2022, 29(20): 52-54转69.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I20/52

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