蒲公英赛醇保护胃上皮细胞及抗炎作用的研究进展

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Abstract With the development of society and irregular sleep, gastric mucosal lesions caused by fast-paced life have become a very common situation. At present, various acid suppressors and mucosal protectants used in clinical treatment of gastric mucosal lesions have achieved certain effect, but there are often various adverse reactions in the treatment process. The results show that the Dandelion resource is very abundant in our country, contain a variety of active ingredients, has extensive pharmacological effect, including the Taraxerol in protecting gastric epithelial cells and anti-inflammatory has significant curative effect, especially in the eradication of Helicobacter pylori, treatment is more simple, and side effect of small, use it as a protection of gastric epithelial cells and anti-inflammatory effect of drugs has important clinical significance. Its effect and mechanisms are mainly accomplished by interfering cell signal transduction, inducing inflammation-related enzymes, regulating cytokines, inhibiting gastric acid and killing Helicobacter pylori. In order to provide a theoretical basis for the therapeutic effect of this drug, the protective effect and anti-inflammatory effect of this drug were systematically reviewed in this paper.

Key words： Taraxerol Gastric pithelial cells Anti-inflammation Signal transduction Cytokines Helicobacter pylori

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	DUAN Huichun
	PU Huayun▲

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DUAN Huichun,PU Huayun▲. Research progress of Taraxerol in protecting gastric epithelial cells and anti-inflammatory effect[J]. 中国当代医药, 2022, 29(20): 30-34.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I20/30

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