中药结肠透析联合尿毒清颗粒对慢性肾脏病3～5期患者疗效及肾功能指标的影响

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Abstract Objective To investigate the curative effect of traditional Chinese medicine colon dialysis combined with Uremic Clearance Granules effect and on the renal function indexes in patients with stage 3-5 chronic kidney disease. Methods A total of 82 patients with stage 3-5 chronic kidney disease in the First People′s Hospital of Jiujiang City from January 2019 to January 2021 were selected as the objects, and they were divided into the routine group (41 cases) and the study group (41 cases) by random number table method. The routine group was treated with oral Uremic Clearance Granules, while the study group was treated with traditional Chinese medicine colon dialysis on the basis of the routine group. Chinese medicine symptom score before and after treatment, clinical efficacy after treatment, the levels of blood uric acid (UA), serum creatinine (SCr), blood urea nitrogen (BUN) before and after treatment, and occurrence of adverse reactions were compared between the two groups. Results After treatment, the main symptom score, secondary symptom score and total score of the two groups were lower than those before treatment, and the main symptom score, secondary symptom score and total score of the study group were lower than those of the routine group, the differences were statistically significant (P<0.05). The overall treatment efficiency rate of the study group was higher than that of the routine group, the difference was statistically significant (P<0.05). After treatment, the levels of blood UA, SCr, BUN in the two groups were lower than those before treatment, and the levels of blood UA, SCr, BUN in the study group were lower than those in the routine group, and the differences were statistically significant (P<0.05). There was no significant difference in the incidence of total adverse reactions during treatment between the two groups (P>0.05). Conclusion Traditional Chinese medicine colon dialysis combined with Uremic Clearance Granules in the treatment of patients with stage 3-5 chronic kidney disease can improve clinical symptoms, improve curative effect and improve renal function, which is safe and has certain popularization value.

Key words： Traditional Chinese medicine colon dialysis Uremic Clearance Granules Serum creatinine Urea nitrogen

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	YAN Huimin
	TONG Wei
	QIU Guoping▲

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YAN Huimin,TONG Wei,QIU Guoping▲. with Uremic Clearance Granules and its effect on renal function indexes in patients with stage 3-5 chronic kidney disease[J]. 中国当代医药, 2022, 29(19): 105-108.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I19/105

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