|
|
|
| Correlation between serum lipid, calcium and phosphorus and hS-CRP level in hemodialysis patients with microinflammation |
| LYU Junzhi |
| The Third Department of Internal Medicine, Second People′s Hospital of Shanwei, Shanwei Yihui Foundation Hospital |
|
|
|
|
Abstract bjective To explore the correlation between metabolism of blood lipid, calcium, and phosphorus and highsensitivity C-reactive protein (hs-CRP) level in hemodialysis patients at the micro-inflammatory state. Methods Fiftyeight patients with microinflammation who received hemodialysis treatment in the Second People′s Hospital of Shanwei from January 2019 to April 2020 were selected as the dialysis group, and 60 healthy volunteers who received physical examination during the same period were selected as the control group. hs-CRP, urine protein, serum creatinine (SCr),blood urea nitrogen (BUN), triglyceride (TG), serum total cholesterol (TC), high density lipoprotein cholesterol (HDL),low density lipoprotein cholesterol (LDL), blood calcium, blood phosphorus and parathyroid hormone (PTH) were compared between the two groups. The correlation of blood lipid, calcium and phosphorus with hs-CRP was analyzed. Results The levels of hs-CRP, SCr, BUN, TC, blood calcium, blood phosphorus, calcium phosphorus product and PTH in dialysis group were higher than those in control group, while HDL was lower than control group, the differences were statistically significant (P＜0.05). There were no significant differences in TG and LDL levels between the two groups(P＞0.05). There was no correlation between serum lipid, calcium and phosphorus levels and hs-CRP in hemodialysis patients (P＞0.05). Conclusion When long-term hemodialysis patients are in a micro-inflammatory state, there are certain abnormalities in blood lipid levels and calcium and phosphorus levels, but the abnormal conditions are not significantly related to hs-CRP.
|
|
|
|
|
|
| [1] |
单婵娟，龙俊睿，邬碧波，等.上海市社区人群对慢性肾脏病的关注度及其影响因素[J].第二军医大学学报，2018，39（1）：37-43.
|
| [2] |
毕礼明，陈英兰，陈亚峰，等.从病例谈经方干预血液透析相关并发症的策略[J].中国中药杂志，2018，43（12）：64-67.
|
| [3] |
钟广芝，胡鹏飞.血液透析患者血清铁调素、转铁蛋白受体含量与铁缺乏、微炎症反应的相关性[J].海南医学院学报，2018，24（1）：30-33.
|
| [4] |
马鸿雁，徐长妍，张冬艳，等.维持性血液透析患者肺炎衣原体感染与动脉粥样硬化的关联性分析[J].中华医院感染学杂志，2018，28（13）：28-31.
|
| [5] |
赵俊丽，朱君君，邵霞，等.血液透析患者颈动脉内中膜厚度与血栓调节蛋白、炎症因子及心血管疾病的关联[J].肾脏病与透析肾移植杂志，2018，27（1）：24-28.
|
| [6] |
付志辉.终末期肾病合并心力衰竭患者维持性血液透析微炎症状态与营养状况、心功能的相关性[J].中国当代医药，2021，28（8）：55-58.
|
| [7] |
Sirich TL，Plummer NS，Gardner CD，et al.Effect of increasing dietary fiber on plasma levels of colon-derived solutes in hemodialysis patients[J].Clin J Am Soc Nephrol，2014，9（9）：1603-1610.
|
| [8] |
赵成群，杨世峰，高青青.慢性肾衰竭维持性血液透析患者血浆致动脉硬化指数与炎性因子及心血管疾病的相关性[J].临床误诊误治，2019，32（4）：85-89.
|
| [9] |
曹倩颖，李向楠，李忠心.不同血液透析方法对老年维持性血液透析患者体内微炎症和营养状态的影响观察[J].临床和实验医学杂志，2018，17（14）：92-95.
|
| [10] |
罗华荣，查艳.慢性肾脏病患者蛋白质能量和脂质水平紊乱地研究进展[J].临床肾脏病杂志，2018，18（10）：590-592，610.
|
| [11] |
Shavit L，Mikeladze I，Torem C，et al.Mild hyponatremia is associated with functional and cognitive decline in chronic hemodialy-sispatients[J].Clin Nephrol，2014，82（5）：313-319.
|
| [12] |
成艺坪，周新丽，景斐，等.成人1 型糖尿病患者甲状腺功能与糖脂水平的关系研究[J].中华内科杂志，2021，60（1）：51-54.
|
| [13] |
胡波，商义，李蓓睿.尿毒症血液透析患者外周血单核细胞Nrf2、NQO1 及血清TNF-α、IL-6 的表达变化及意义[J].中国血液净化，2018，17（5）：299-303.
|
| [15] |
陈彦伊，刘舒苏，王少侠，等.维持性血透患者的原发病及血管通路应用变迁[J].中国中西医结合肾病杂志，2020，21（6）：51-53.
|
| [16] |
刘丽茹，何敏华.维持性血液透析患者钙磷水平及甲状旁腺素水平横断面调查[J].临床肾脏病杂志，2018，18（1）：25-29.
|
| [17] |
黄盈.低钙透析对维持性血液透析患者钙磷水平及甲状旁腺激素影响的Meta 分析[J].中国血液净化，2019，18（1）：21-25.
|
| [18] |
茶春丽，李靖娟，陈国姝，等.透析患者微炎症状态与血脂水平及钙磷水平的相关性[J].昆明医科大学学报，2017，38（1）：41-45.
|
| [19] |
付慧，袁长秀，谭屿娜.血液透析与血液灌流联合治疗对长期血液透析患者微炎性因子及钙磷水平的影响[J].医学理论与实践，2016，29（18）：3208-3209.
|
| [14] |
Taslipinar A，Yaman H，Yilmaz MI，et al.The relationship between inflammation，endothelial dysfunction and proteinuria in patients with diabetic nephropath[J].Scand J Clin Lab Invest，2011，71（7）：606-612.
|
| [20] |
李强.维持性腹膜透析患者微炎症出现的特点分析及其临床干预方法归纳研究[J].中国医药科学，2020，10（13）：199-202.
|
|
|
|
