|
|
Analysis of related factors of drug compliance in rehospitalized schizophrenia patients |
WANG Hongjie1 ZHU Lingqun2 WANG Zhimin3 LI Xianbin3 ZHANG Yuxia1 ▲ SUN Yanping1 TAN Liping1 XIA Lijie1 |
1. Department of Psychiatry, Huairou Anjia Hospital
2. Department of Encephalopathy,Dongzhimen Hospital
3. Department of Psychiatry,Beijing Anding Hospital |
|
|
Abstract Objective To explore the related factors of drug compliance in rehospitalized patients with schizophrenia.Methods A total of 180 cases of hospitalized patients with schizophrenia′s age, gender, duration, marriage, employment, cultural degree, family history, living environment, the types of drugs, self-knowledge, severe mental illness risk grading, medication, economic situation, disability identification information free of charge from May 2016 to May 2018 in Huairou Anjia Hospital, Beijing were retrospective analysed. The Morisky adherence questionnaire (MAQ-8) was applied, and the adherence score<6 was divided into the poor adherence group (112 cases), score of 6-8 points was divided into the adherence group (68 cases). Logistic regression analysis were used to explore the related factors of drug compliance in rehospitalized patients with schizophrenia. Results The single factor analysis showed that employment status, living environment, drug type, self-awareness and risk of severe mental illness were the influencing factors of poor compliance of re-hospitalized patients the differences were statistically significant (P<0.05). Logistic regression analysis showed that lack of self-awareness (β=1.338, OR=3.811, 95%CI=2.362-6.148), risk rating of severe mental illness grade≥2 (β=1.213, OR=3.363, 95%CI=1.558-7.262) were independent risk factors for medication compliance of rehospitalized schizophrenia patients (P<0.05). Conclusion The worse the self-awareness of patients with schizophrenia is, the worse the compliance is. The higher the risk assessment grade of severe mental illness is, the worse the compliance is. Therefore, clinical medical staff should pay attention to the self-awareness of patients and timely assess the risk grade of severe mental illness, which will help to improve the treatment compliance of patients.
|
|
|
|
|
[1] |
Qweb MJ,Sawa A,Mortensen PB.Schizophrenia[J].Lancet,2016,388(10039):86-97.
|
[2] |
陆林.沈渔邨精神病学[M].北京:人民卫生出版社,2017:301.
|
[3] |
冷海霞,朱玥,王菲,等.精神分裂症高危人群的认知功能与焦虑、抑郁及精神病性症状[J].神经疾病与精神卫生,2020,20(1):21-26.
|
[5] |
向锋,梁平欣,林秀菊.综合干预对社区精神分裂症患者社会功能和服药依从性的影响[J].中国实用医药,2018,13(35):181-182.
|
[8] |
王龙,张晓梅,罗滨,等.精神分裂症复发因素分析[J].临床合理用药杂志,2020,13(1):131-133.
|
[9] |
王智慧.ICD-10 精神与行为障碍分类疑难编码与错码成因分析[J].人人健康,2020(14):99.
|
[10] |
俞吉,冉烁,徐玲.Morisky 用药依从性量表8 条目在老年慢性病患者用药评价中的应用[J].临床药物治疗杂志,2020,18(11):63-66.
|
[4] |
Liu D,Cen H,Jiang K,et al.Ressearch progress in biological studies of schizophrenia in china in 2017[J].Shanghai Arch Psychiatr,2018,30(3):147-153.
|
[6] |
Tham XC,Xie H,Chng CM,et al.Factors affecting medication adherence among adults with schizophrenia:A literaturere-View[J].Arch Psychiatr Nurs,2016,30(6):797-809.
|
[7] |
Leucht S,Tardy M,Komossa K,et al.Antipsychotic drugs versus placebo for relapse prevention in schizophrenia:a systematic review and meta-analysis[J].Lancet,2012,379(9831):2063-2071.
|
[11] |
寸金芝,赵丽琴.Morisky 问卷评价精神分裂症恢复期患者服药依从性的信度和效度[J].临床精神医学杂志,2016,26(3):185-186.
|
[12] |
聂莲莲,潘胜琼,吴龙辉.居家精神分裂症患者服药依从性影响因素分析[J].预防医学,2019,31(12):1283-1286.
|
[13] |
张明园,何燕玲.精神科评定量表手册[M].6 版.长沙:湖南科学技术出版社,2015:477-480.
|
[14] |
中华人民共和国国家卫生健康委员会.严重精神障碍管理治疗工作规范(2018年版)[Z].2018.
|
[15] |
Phan SV.Medication adherence in patients with schizophrenia[J]Int J Psychiatry Med,2016,51(2):211-219.
|
[16] |
曾繁丽,刘鹏程,蒋鹏,等.1218 例严重精神障碍患者监护人照顾负担现状及影响因素的调查分析[J].中华护理杂志,2019,54(1):95-99.
|
[17] |
Phan SV.Medication adherence in patients with schizophrenia[J].Int J Psychiatry Med,2016,51(2):211-219.
|
[18] |
蔡清艳,张岚,王钰,等.精神分裂症患者再入院研究进展[J].临床精神医学杂志,2019,29(5):353-355.
|
[19] |
Gray R,Bressington D,Ivanecka A,et al.Is adherence therapy an effective adjunct treatment for patients with schizophrenia spectrum disorders?A systematic review and meta-analysis[J].BMC Psychiatry,2016,16(6):90-91.
|
[20] |
姜涛,王智民,郭志华,等.北京市怀柔区社区严重精神障碍患者免费服药依从性相关因素分析[J].神经疾病与精神卫生,2020,20(12):849-854.
|
[21] |
徐良雄,高卉,曾德志,等.200 例精神分裂症患者服药依从性的相关影响因素分析[J].湖北科技学院学报(医学版),2015,29(5):395-397.
|
[22] |
郑家仁,李长远,潘洪润,等.社区重性精神病患者危险性评估及影响因素分析[J].海峡预防医学杂志,2017,23(4):39-41.
|
[23] |
张红梅,吴爱勤.社区重性精神疾病患者肇事肇祸危险性分析[J].国际精神病学杂志,2013,40(3):145-148.
|
[24] |
陈良虎,汪燕,姚琳,等.上海郊区首发精神分裂症住院患者家庭负担及家属心理健康状况与患者自知力的关系[J].中国健康心理学杂志,2017,25(8):1134-1138.
|
[25] |
张萍,栗克清,司天梅.精神分裂症患者的家庭负担及其与服药依从性的关系[J].大连医科大学学报,2016,38(2):129-133.
|
[26] |
Chandra IS,Kumar KL,Reddy MP,et al.Attitudes toward Medication and Reasons for Non-Compliance in Patients with Schizophrenia[J].Indian J Psychol Med,2014,36(3):294-298.
|
|
|
|