补嘘养勒糖浆对产后缺乳模型大鼠治疗作用的研究

Abstract
Figure/Table
References (20)
Related Citation (5)

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the therapeutic effect of Buxu Yangle Syrup (BXYL) on Bromocriptine mesylate induced lactation deficiency in rats. Methods Bromocriptine mesylate was used to establish a rat model of lactation deficiency. The body weight and lactation of the offspring were recorded. The serum prolactin was detected by enzyme linked immunosorbent assay (ELISA). The histopathological changes of hypophysis and mammary gland were observed.Results The body weight and growth rate of the BXYL high and medium dose groups were higher than those of the model group, and the differences were statistically significant (P＜0.05). The 8 h lactation per day of the BXYL high,medium and low dose groups on the 3-10 d after delivery were higher than those of the model group, and the differences were statistically significant (P＜0.01). The serum quercetin levels in the BXYL high and medium dose groups on the 3rd, 7th, and 11th days after delivery were higher than those in the model group, and the differences were statistically significant (P＜0.05). Compared with the model group, the number of mammary acini and ducts in each dose group of BXYL increased significantly, expanded and proliferated, and the adipose connective tissue between mammary lobules decreased. Compared with the model group, the morphology of pituitary cells in each dose group of BXYL was normal, and eosinophils increased. Conclusion Buxu Yangle Syrup has obvious effect on promoting lactation in rats with lactation deficiency.

Key words： Buxu Yangle Syrup Postpartum hypogalactia Lactogenesis Prolactin

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LI Na
	LI Qingping
	CHEN Xiaoyi
	HUANG Xiaotong
	FANG Gang

Cite this article:

LI Na,LI Qingping,CHEN Xiaoyi, et al. Study on therapeutic effect of Buxu Yangle Syrup on bromocriptine mesylate induced hypogalactia in rats[J]. 中国当代医药, 2022, 29(16): 57-60转64.

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I16/57

[2]	张璐，杭林涛，刘春燕，等.产后缺乳的中医证候规律研究[J].湖南中医杂志，2020，36（7）：120-121.
[3]	徐晓萌，王劲.自制通乳膏穴位贴敷治疗气血虚弱型产后缺乳53 例[J].黑龙江中医药，2018，47（1）：63-64.
[4]	林玲，张阳.催乳汤治疗产后缺乳400 例分析[J].中医药学刊，2004，22（4）：680.
[5]	黄溥玮，卢健棋，林浩，等.中药五指毛桃的化学成分、药理作用及临床应用研究进展[J].辽宁中医药大学学报，2020，22（12）：93-96.
[6]	中华人民共和国药典委员会.中华人民共和国药典[M].北京：中国医药科技出版社，2020：139.
[7]	袁志超，汪芳安.番木瓜的开发应用及研究进展[J].武汉工业学院学报，2006（3）：15-20.
[8]	国家药典委员会.中华人民共和国药典[S].北京：中国医药科技出版社，2020：162.
[9]	王一乔，王成龙，韦宁华，等.壮医药防治产后病的研究进展[J].中国民族医药杂志，2020，26（7）：62-64.
[10]	玉华，杨润文，杨美春，等.壮医毛桃归藤饮促进产后康复的临床观察[J].大医生，2018，3（Z1）：75-76.
[1]	张璐，杭林涛，刘春燕，等.产后缺乳的病因研究[J].中国中医药现代远程教育，2020，18（19），58-60.
[11]	郑集美，吴飞鹏，蔡明媚，等.当归芍药散在乳腺癌患侧上肢淋巴水肿的临床应用[J].亚太传统医药，2021，17（2）：81-84.
[12]	何丽敏.中医治疗产后缺乳方剂用药特点研究[D].昆明：云南中医药大学，2020.
[13]	Martin CR，Ling PR，Blackburn GL.Review of Infant Feeding：Key Features of Breast Milk and Infant Formula[J].Nutrients，2016，8（5）：279.
[14]	Andreas NJ，Kampmann B，Mehring Le-Doare K.Human breast milk：A review on its composition and bioactivity[J].Early Hum Dev，2015，91（11）：629-635.
[15]	Palmeira P，Carneiro-Sampaio M.Immunology of breast milk[J].Rev Assoc Med Bras，2016，62（6）：584-593.
[16]	Freeman ME，Kanyicska B，Lerant A，et al.Prolactin：structure，function，and regulation of secretion[J].Physiol Rev，2000，80（4）：1523-1631.
[17]	Alex A，Bhandary E，McGuire KP.Anatomy and Physiology of the Breast during Pregnancy and Lactation [M].Adv Exp Med Biol，2020，1252：3-7.
[18]	Augustine RA，Ladyman SR，Bouwer GT，et al.Prolactin regulation of oxytocin neurone activity in pregnancy and lactation[J].J Physiol，2017，595（11）：3591-3605.
[19]	王立新，韩桂俊，薛峰.孕产妇泌乳素影响因素与干预措施研究[J].河北医药，2015，37（22）：3439-3441.
[20]	胡慧丽，陈珂琪，王璞.产后超早期乳房按摩结合穴位按摩对初产妇泌乳量及血清泌乳素水平的影响[J].包头医学院学报，2020，36（12）：92-94.