骨骼肌衰老对腰痛发病的影响

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Abstract Low back pain is a common disease, it′s incidence and outcome are closely related to the stability of lumbar spine. The pathogenesis of low back pain is still unclear, and previous studies on the pathogenesis of low back pain mostly focus on the osteoarticular system and nervous system. With the proposal of the concept of skeletal muscle aging and the development of spinal biomechanics and anatomy, scholars began to explore the pathologic mechanism of skeletal muscle aging in the waist and its interaction with pathological changes in the spine. Studies have shown that a series of pathological changes of skeletal muscle caused by aging, such as systemic low-grade inflammation, senile obesity, sarcopenia and physiological and biochemical changes, may be the key factors to induce low back pain. Based on this, through the consult relevant literature and research in recent years, the author trying to discuss the incident of low back pain from the angle of skeletal muscle ageing, and summarize the correlation between skeletal muscle aging in the waist and the low back pain, so as to provide effective reference for the future medical biology research.

Key words： Low back pain Aging Skeletal muscle aging Sarcopenia

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	Articles by authors
	JIN Jing
	CHEN Yimin
	LIN Jianping
	GUO Mingling
	GOU Yanyun
	CHEN Shaoqing
	WANG Hong

Cite this article:

JIN Jing,CHEN Yimin,LIN Jianping, et al. Effect of skeletal muscle aging on low back pain[J]. 中国当代医药, 2022, 29(16): 39-43.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I16/39

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