超微通道与微通道经皮肾镜治疗>2 cm的肾结石患者的效果及安全性分析

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Abstract Objective To investigate the efficacy and safety of supermicro percutaneous channel nephrolithotripsy and micro percutaneous channel nephrolithotripsy in the treatment of patients with kidney stones with diameter ＞2 cm.Methods A total of 40 patients with kidney stones with diameter ＞2 cm who were admitted to Foshan Fuxing Chancheng Hospital from January 2016 to December 2020 were selected as the research subjects. They were divided into the observation group and the control group by the random number table method, with 20 patients in each group.The observation group was treated with supermicro percutaneous channel nephrolithotripsy, while the control group was treated with micro percutaneous channel nephrolithotripsy. The stone clearance rate (SFR) of 3 d after surgery was compared between the two groups. The intraoperative channel establishment time, lithotripsy time, whole surgery time and hospital stay were compared between the two groups. The levels of hemoglobin (Hb), serum creatinine (SCr), Creactive protein (CRP) and procalcitonin (PCT) in the two groups before and after surgery were compared. The incidence of postoperative complications (bleeding and fever) was compared between the two groups. Results There was no significant difference in SFR between the two groups (P＞0.05). The intraoperative channel establishment time in observation group was shorter than that in control group, the lithotripsy time and whole surgery time were longer than those in control group, with statistically significant differences (P＜0.05). There was no significant difference in the length of hospital stay between the two groups (P＞0.05). Before surgery, there were no significant differences in the levels of SCr, CRP, PCT and Hb between the two groups(P＞0.05).After surgery,there were no significant differences in the levels of SCr, CRP and PCT between the two groups (P＞0.05). The Hb level in observation group was higher than that in control group, the difference was statistically significant (P＜0.05). The SCr, CRP, PCT levels in the two groups after operation were higher than those before surgery, and Hb levels in the two groups after operation were lower than those before surgery, the differences were statistically significant (P＜0.05). There was no significant difference in the total incidence of postoperative complications between the two groups (P＞0.05). Conclusion Supermicro percutaneous channel nephrolithotripsy and micro percutaneous channel nephrolithotripsy are both efficient and safe lithotriptic methods, and no significant differences are observed in the incidences of postoperative SFR and complications between the two. However, supermicro percutaneous channel nephrolithotripsy is recommended for clinical application due to its relatively short time of establishing channels and less damage to tissues.

Key words： Kidney stone;Supermicro percutaneous channel nephrolithotripsy;Micro percutaneous channel nephrolithotripsy Safety Therapeutic effect

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	TAN Rizhao

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TAN Rizhao. Analysis on efficacy and safety of supermicro percutaneous channel nephrolithotripsy and micro percutaneous channel nephrolithotripsy in patients with kidney stones with diameter ＞2 cm[J]. 中国当代医药, 2022, 29(16): 15-19转24.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I16/15

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