Correlation analysis of sex hormone, blood lipid and body mass index with anti-mullerian hormone abnormality in patients with polycystic ovarian syndrome
WANG Jing
Department of Laboratory Medicine, Maternal and Child Health Care Hospital of Ganzhou City, Jiangxi Province,Ganzhou 341000, China
AbstractObjective To investigate the correlation of sex hormone, blood lipid and body mass index (BMI) with antimullerian hormone (AMH) abnormality in patients with polycystic ovarian syndrome (PCOS). Methods A total of 50 patients with PCOS who admitted to the hospital from January 2018 to December 2019 as the research objects were included in observation group, and 50 healthy controls during the same period in our hospital were included in control group. The AMH, sex hormones (luteinizing hormone [LH], follicle stimulating hormone [FSH], prolactin [PRL], estradiol [E2], testosterone [TESTO], progesterone [PROG]), blood lipid (total cholesterol [CHOL], triglyceride [TG]) contents and BMI of all PCOS patients and healthy controls were measured in serum samples from both groups, and the correlation of sex hormone, blood lipid, BMI and AMH in PCOS patients were analyzed. Results The BMI, LH, E2, TESTO,CHOL, TG and AMH in observation group were higher than those in control group, and the PRL, FSH, PROG in observation group were lower than those in control group, and the differences were statistically significant (P＜0.05). Pearson analysis showed that the levels of BMI, LH, E2, TESTO, CHOL and TG in PCOS patients were positively correlated with AMH (r＞0, P＜0.05). The PRL, FSH and PROG were negatively correlated with AMH (r＜0, P＜0.05). Conclusion The serum AMH has certain correlation with sex hormone (LH, FSH, PRL, E2, TESTO, PROG), blood lipid (CHOL, TG) and BMI in patients with PCOS. Therefore, early screening, treatment and prevention for PCOS patients have certain clinical significance.
WANG Jing. Correlation analysis of sex hormone, blood lipid and body mass index with anti-mullerian hormone abnormality in patients with polycystic ovarian syndrome[J]. 中国当代医药, 2020, 27(25): 190-193.
