冷刀锥切术、宫腔镜下宫颈锥切术和宫腔镜辅助宫颈冷刀锥切术在高级别宫颈上皮内瘤变中的应用

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Abstract Objective To investigate the application of cold knife conization (CKC), transvaginal cone-resection of cervix uteri (TCRC) and hysteroscopic coagulation adjuvant cold knife conization (HCKC) in high-grade squamous intraepithelial lesion(HSIL).Methods The clinical data of 118 patients with HSIL who underwent surgical treatment in our hospital from January 2016 to August 2018 were retrospectively analyzed, and they were divided into the CKC group(38 cases), the TCRC group (46 cases) and the HCKC group (32 cases) according to different surgical methods. The CKC group was treated with CKC, the TCRC group was treated with TCRC, and the HCKC group was treated with HCKC.The clinical efficacy, perioperative conditions, the coincidence rate of pathological diagnosis and the total incidence of complications were compared among the three groups. Results There were no statistically significant differences between the three groups in lesion clearance rates and length of stay (P＞0.05). The operation time of the HCKC group and the TCRC group was shorter than that of the CKC group, and the intraoperative blood loss of the HCKC group and the TCRC group was less than that of the CKC group, the differences were statistically significant (P＜0.05). There was no significant difference in hospitalization time among the three groups (P＞0.05). There was statistically significant difference among the three groups in pathological diagnosis (P＜0.05). There were no significant differences in the total incidence of postoperative bleeding, cervical stenosis, abnormal menstruation, repeated abdominal pain and other complications among the three groups (P＞0.05). Conclusion CKC, TCRC and HCKC are all effective treatment methods for HSIL patients. HCKC has the advantages of short operative time, low intraoperative blood loss and high coincidence rate of pathological diagnosis, which is worthy of further promotion.

Key words： High-grade cervical intraepithelial neoplasia Cold knife conization Transvaginal cone-resection of cervix uteri Hysteroscopic coagulation adjuvant cold knife conization

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	ZENG Qiu-ping
	LI Xiao-xia
	CHEN Qiao-feng

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ZENG Qiu-ping,LI Xiao-xia,CHEN Qiao-feng. Application of cold knife conization, transvaginal cone-resection of cervix uteri and hysteroscopic coagulation adjuvant cold knife conization in high-grade squamous intraepithelial lesion[J]. 中国当代医药, 2020, 27(25): 124-127.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2020/V27/I25/124

[1]	左学骞，舒丽莎.女性宫颈病变、人乳头瘤病毒感染及相关危险因素研究进展[J].中国妇幼保健，2014，29（32）：5352-5355.
[2]	蒋燕明.宫颈上皮内瘤变的进展预警[J].国际妇产科学杂志，2018，45（1）：71-75.
[3]	胡淑霞，梅丽，王志慧.宫颈锥切术治疗宫颈上皮内瘤变的临床疗效观察[J].中国妇幼保健，2015，30（6）：960-962.
[4]	毕蕙，张小松，王海平，等.阴道镜下不同活检方法在高级别子宫颈上皮内病变检出中的作用[J].中国妇产科临床杂志，2017，18（6）：9-13.
[5]	夏玲芳，吴小华.阴道上皮内瘤变的诊断与治疗[J].中华妇产科杂志，2011，46（1）：73-75.
[6]	崔虹飞.HPV 基因分析在宫颈上皮内瘤变中的作用和意义[D].青岛：青岛大学，2013.
[7]	宋学红.三阶梯诊疗程序筛查诊治宫颈癌前病变[J].中国实用妇科与产科杂志，2007，23（7）：499-501.
[8]	兰岚，黄冬梅，邓克红，等.高级别宫颈上皮内瘤变的临床诊治分析[J].实用妇产科杂志，2013，29（2）：140-144.
[9]	苑占娜，陈绍正，程香红，等.宫颈冷刀锥切术联合滚球射频电凝止血治疗宫颈上皮内瘤变观察[J].国际妇产科学杂志，2014，41（4）：384-385.
[10]	刘木彪，侯桂玉，何援利，等.宫腔镜下宫颈锥切术治疗宫颈上皮内瘤变Ⅲ级术后及远期疗效观察[J].南方医科大学学报，2012，32（5）：687-690.
[11]	向安玲，董晓静，龚元杰.宫颈环形电切术与冷刀锥切术治疗宫颈上皮内瘤变疗效比较的Meta 分析[J].实用妇产科杂志，2011，27（5）：371-374.
[12]	朱尽秀.宫颈环形电切术与宫颈冷刀锥切术治疗高级别上皮内瘤变的临床效果及妊娠结局[J].临床医药文献电子杂志，2017，4（44）：8591-8591.
[13]	陈梅庄，蔡慧华，刘木彪，等.两种电切方法对宫颈标本切缘病理诊断影响对比研究[J].中国实用妇科与产科杂志，2018，34（6）：86-89.
[14]	张赛男，熊翔鹏，王观凤，等.3 种不同宫颈锥切方式治疗宫颈高级别上皮内瘤变的效果比较[J].广东医学，2017，38（22）：3475-3477.
[15]	崔柳柳.不同宫颈锥切方法治疗宫颈上皮内瘤变Ⅲ级患者的效果观察[J].临床合理用药杂志，2017，10（29）：16-17.