|
|
Analysis of the influencing factors of premature cerebral infarction |
LIN Yufeng1 HUANG Xinghong2 CHEN Dongling1 LI Yangyang1 XU Qiugui1 |
1.Department of Laboratory Medicine,Yangjiang People′s Hospital,Guangdong Province,Yangjiang 529500,China;
2.Department of Obstetrics,Yangjiang People′s Hospital,Guangdong Province,Yangjiang 529500,China |
|
|
Abstract Objective To explore the influencing factors of premature cerebral infarction.Methods The clinical data of 106 patients with acute cerebral infarction treated in Yangjiang People′s Hospital from July 2019 to July 2021 were analyzed retrospectively,they were divided into premature cerebral infarction group (n=49) and non premature cerebral infarction group (n=57) according to the age of onset.The clinical data and familial hypercholesterolemia (FH) and blood lipid indexes of the two groups were compared,and multivariate logistic regression analysis was used for premature cerebral infarction.Results The prevalence of FH in premature cerebral infarction group was higher than that in non premature cerebral infarction group,the difference was statistically significant (P<0.05).The multivariate logistic regression analysis showed that history of stroke (OR=1.92,95%CI:1.84-3.29),history of hypertension (OR=1.38,95%CI:1.84-1.69),triglyceride (TG) (OR=1.83,95%CI:1.36-4.89),low density lipoprotein cholesterol (LDL-C) (OR=1.79,95%CI:1.34-4.39) and FH (OR=1.98,95%CI:1.70-3.61) are the independent risk factors of premature cerebral infarction.Conclusion FH and blood lipid indexes are independent risk factors of premature cerebral infarction.Clinically,we can prevent premature cerebral infarction by diagnosing FH and controlling blood lipid level.
|
|
|
|
|
[1] |
苏斌杰,车文良.家族性高胆固醇血症诊治进展[J].岭南心血管病杂志,2018,24(3):361-364.
|
[2] |
彭道泉,赵水平.中国家族性高胆固醇血症诊疗现状及进展[J].中国循环杂志,2020,35(4):411-416.
|
[3] |
姚纯,赵水平.家族性高胆固醇血症诊治新进展[J].临床心血管病杂志,2019,35(12):1075-1079.
|
[4] |
邱惠,李虹伟.家族性高胆固醇血症的诊治进展[J].心肺血管病杂志,2020,39(8):1011-1015.
|
[5] |
杨华,张炎,鲍治诚,等.醒脑静注射液联合西药治疗对脑梗死患者脑血管血流指标及神经功能指标的影响[J].世界中西医结合杂志,2019,14(4):561-563,566.
|
[6] |
崔淯夏,梁文卿,李素芳,等.家族性高胆固醇血症的诊断现状与挑战[J].中华老年心脑血管病杂志,2019,21(7):766-768.
|
[7] |
曾宏亮,刘俊杰,胡玲.早发性脑梗死与家族性高胆固醇血症的相关性研究及临床特点分析[J].现代医院,2019,19(11):1659-1660,1663.
|
[8] |
丁雅明,丁亚娜,孙婉琴,等.从中国家族性高胆固醇血症患者的诊断及治疗现状谈慢病管理[J].中国老年学杂志,2020,40(17):3803-3807.
|
[9] |
李格轩,刘巍,王旭,等.早发冠心病患者中家族性高胆固醇血症的冠脉特点与心功能相关性分析[J].标记免疫分析与临床,2019,26(11):1801-1804.
|
[10] |
姜丽红,刘戈力.家族性高胆固醇血症的诊疗进展[J].天津医药,2019,47(9):998-1002.
|
[11] |
卓杰.高胆固醇血症对神经功能和脑血管病影响的研究进展[J].中国现代神经疾病杂志,2021,21(2):107-113.
|
[12] |
徐凯,刘莉.家族性高胆固醇血症的临床特点及其与早发心肌梗死的关系[J].岭南心血管病杂志,2019,25(6):601-605.
|
[13] |
葛怡兰,刘佳敏,高岩,等.中国家族性高胆固醇血症诊疗现状[J].中国动脉硬化杂志,2018,26(8):851-857.
|
[14] |
宋阳春,车文良.家族高胆固醇血症的发病、诊断及治疗[J].中国临床研究,2019,32(1):121-125.
|
[15] |
武文峰,孙立元,温文慧,等.家族性高胆固醇血症患者突变基因及低密度脂蛋白受体活性分析[J].中国医药,2018,13(7):965-968.
|
|
|
|