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| Clinical effect of self-made Bushen Jianpi Antai Decoction in the treatment of threatened abortion with subclinical hypothyroidism |
| LIANG Yan |
| Department of Traditional Chinese Medicine, Maternal and Child Health Hospital of Jiangxi Province, Nanchang 330000, China |
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Abstract Objective To explore the clinical effect of self-made Bushen Jianpi Antai Decoction in the treatment of threatened abortion with subclinical hypothyroidism. Methods A total of 100 patients with threatened abortion combined with subclinical hypothyroidism in Maternal and Child Health Hospital of Jiangxi Province from August 2020 to March 2021 were selected as the research objects, and they were divided into the test group (50 cases) and the control group(50 cases) according to the random number table method. Both groups were treated with Progesterone Injection, the control group was treated with Levothyroxine Sodium Tablets, and the test group was treated with self-made Bushen Jianpi Antai Decoction on the basis of the control group. Both groups were treated for 30 days. The clinical efficacy after treatment and the levels of pregnancy hormone and thyroid function indexes before and after treatment were compared between the two groups. Results The total clinical effective rate after treatment in the test group was 88.00%,which was higher than 70.00% in the control group, the difference was statistically significant (P＜0.05). After treatment,the serum blood human chorionic gonadotropin (HCG), progesterone (P), estradiol (E2) levels in the two groups were higher than those before treatment, and the levels of HCG, P, E2 in the test group after treatment were higher than those in the control group, the differences were statistically significant (P＜0.05). The serum thyroid stimulating hormone(TSH) levels in the two groups after treatment were lower than those before treatment, and the level of TSH in the test group was lower than that in the control group, the differences were statistically significant (P＜0.05). There were no significant differences in the levels of serum free thyroxine (FT4) and free triiodothyronine (FT3) between the two groups before and after treatment (P＞0.05). Conclusion The self-made Bushen Jianpi Antai Decoction can adjust the thyroid function indexes and pregnancy hormone levels of patients with threatened abortion and subclinical hypothyroidism, enhance the therapeutic effect.
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