2016—2020年南通大学附属南通第三医院呼吸内科住院患者抗菌药物使用情况调查

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Abstract Objective To investigate and analyze the use of antibiotics in hospitalized patients in Respiratory Department of Nantong Third Hospital Affiliated to Nantong University from 2016 to 2020, and further strengthen the rational use of antibiotics in respiratory department. Methods According to the requirements of the national special campaign plan for clinical application of antibacterial drugs, prescription automatic screening system (PASS) for rational use of antibiotics in hospital ranked the top 5 in the amount of antibacterial drugs used by inpatients in respiratory department of hospital from 2016 to 2020, the rate of antibacterial drugs used, the intensity of antibacterial drugs used, the rate of microbial samples submitted for examination of inpatients receiving antibacterial drugs, the way of antimicrobial drugs administered statistics and comparison were made on the combined use of antibiotics. Results From 2016 to 2020, the overall consumption of carbapenem antibiotics showed a downward trend, the consumption of Moxifloxacin in quinolone antibiotics decreased year by year, and the consumption of the third generation cephalosporin antibiotics was still at a high level every year, but the consumption of Penicillin and Cephalosporin Enzyme Inhibitors showed an increasing trend year by year. The use rate of antibiotics in inpatients of respiratory medicine decreased year by year, from 89.58% in 2016 to 72.11% in 2020. The use intensity of antibiotics in inpatients of respiratory department also decreased with the decrease of use rate, from 120.94 in 2016 to 89.85 in 2020. The total inspection rate of patients treated with antibiotics, the inspection rate of microbial samples of patients treated with restricted antibiotics and the inspection rate of microbial samples of patients treated with special use antibiotics met the standards every year, and there was an overall upward trend from 2016 to 2020. Intravenous administration was the main mode of administration in hospitalized patients in respiratory department, which was higher than oral administration and other modes of administration. The proportion of single drug use in hospitalized patients in respiratory department was increasing year by year, and the proportion of double, triple and quadruple drugs showed a downward trend as a whole, but the highest proportion was still double drug use. In 2020, the proportion of double drug use had reach 54.67%, which was higher than that of single drug use and other combinations. Conclusion From 2016 to 2020, the utilization rate, use intensity,submission rate and combined use of antibiotics in respiratory department showed continuous improvement.

Key words： Respiratory medicine Antibiotics Rational use of drugs Investigation and analysis

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