中国当代医药
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中国当代医药  2022, Vol. 29 Issue (13): 113-116    DOI:
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Effect of Oxycodone combined with Dexmedetomidine analgesia on uterine contraction and traction pain after cesarean section
SONG Hui LIU Jiaoyang
Department of Pharmacy, Liaoyang City Central Hospital, Liaoning Province, Liaoyang 111000, China
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Abstract  Objective The impacts of Oxycodone combined with Dexmedetomidine analgesia on uterine contraction and traction pain after cesarean section. Methods From October 2018 to December 2019, 104 parturients who gave birth by cesarean section in Liaoyang City Central Hospital were selected as the research objects. According to random number table method, they were divided into observation group and control group, with 52 cases in each group, the observation group was treated with Oxycodone combined with Dexmedetomidine for postoperative analgesia, and the control group was treated with Dexmedetomidine for postoperative analgesia. The visual analogue scale (VAS) score, Ramsay sedation score, incidence of adverse reactions, Edinburgh postpartum depression scale (EPDS) score of two groups in the maternal pain were compared. Results At 6, 12, 24, 48 h after operation, the VAS scores of surgical incision pain and uterine contraction pain of the puerpera in the observation group were lower than those in the control group, the differences were statistically significant (P<0.05). There were no significant differences in the Ramsay sedation score and the total incidence of adverse reactions between the two groups at 2, 4, 6, 12, 24, 48 h after operation (P>0.05).The EPDS scores of two groups after operation were lower than those before operation, and the EPDS score of the observation group was lower than that of the control group, the differences were statistically significant (P<0.05).Conclusion The combination of Oxycodone and Dexmedetomidine has a good analgesic effect after cesarean section. It can effectively reduce postoperative uterine contractions and traction pain, relieve postpartum depression, and have fewer adverse reactions.
Key wordsCesarean section      Oxycodone      Dexmedetomidine      Uterine contraction      Pain     
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