冠状动脉CT血管造影血管斑块特点与狭窄情况预测心肌缺血的效能

Abstract
Figure/Table
References (18)
Related Citation (15)

Download: PDF (705 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the efficacy of coronary CT angiography (CCTA) in predicting myocardial ischemia with Coronary plaque characteristics and stenosis. Methods From January 2019 to December 2020, 88 patients with suspected or known coronary heart disease (196 diseased vessels) admitted to Xianning First People′s Hospital were selected as the study subjects. After admission, all the enrolled patients received CCTA, coronary artery angiography(CAG)and Fractional flow reserve(FFR)examination,and the gold standard was the cardiac FFR value.According to FFR value, they were divided into ischemic group (n=45, 99 vessels with lesion, FFR value ≥0.8) and non-ischemic group(n=43, 97 vessels with lesion, FFR value <0.8). The clinical baseline data of the two groups were retrospectively analyzed, and the characteristics of CCTA plaque and the stenosis of the two groups were compared. The value of THE characteristics of CCTA plaque and the stenosis rate in the diagnosis of myocardial ischemia were analyzed. Results The degree of stenosis in the ischemic group was more severe than that in the non-ischemic group, and the difference was statistically significant (P<0.05). The results showed that the vascular plaque load, plaque volume and calcification score in the ischemic group were higher than those in the non-ischemic group, and the lesion length was lower than that in the non-ischemic group, with statistical significances (P<0.05). CT high-risk plaque and low-density plaque were more than those in the non-ischemic group, with statistical significances (P<0.05). ROC analysis showed that the AUC of CCTA lesion stenosis rate (>75% stenosis), CT high-risk plaque, lesion length and combined detection in predicting myocardial ischemia were 0.626, 0.605, 0.696 and 0.759, respectively. Conclusion CCTA has good efficacy in predicting myocardial ischemia in patients with vascular plaque characteristics and vascular stenosis rate, and the combination of CCTA and CCTA can be used as an important diagnostic index of myocardial ischemia.

Key words： Coronary CT angiography Vascular plaque Vascular stenosis Myocardial ischemia Prediction

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I13/103

[1]	范英兰，胡丽萍，朱竟赫，等.心肌缺血动物模型实验研究进展[J].实验动物科学，2018，35（1）：72-75.
[2]	高艳，顾慧，杨世锋，等.基于冠状动脉CT 血管成像的斑块定量分析及其与心肌缺血损伤的相关性研究[J].中华放射学杂志，2020，54（2）：129-135.
[3]	刘鹏，孙昊洋，姜顺.血流储备分数CT 成像预测冠状动脉临界病变患者功能性心肌缺血的临床价值[J].临床误诊误治，2019，32（5）：73-78.
[4]	王德广，刘猛，马越，等.冠状动脉功能学评价研究进展[J].中国医药，2019，14（6）：153-155.
[5]	张昕，雷智莉.冠状动脉CT 血管造影在心绞痛诊断中的价值[J].山西医药杂志，2020，49（16）：2123-2124.
[6]	杨琳，徐磊，何继强，等.基于CT 的冠状动脉血流储备分数对冠状动脉含钙化病变的诊断评价[J].中华放射学杂志，2019，53（8）：668-674.
[7]	马亚楠，吕滨.2017年ACR 关于高度疑诊冠心病慢性胸痛患者的影像诊断技术适用性标准[J].中国循环杂志，2017，32（2）：169-172.
[8]	耿文磊，胡奉环，尹栋，等.CT 血流储备分数对心肌缺血病变的诊断效能[J].中国医学影像技术，2020，36（2）：171-176.
[9]	王大博.基于CCTA 数据计算的血流储备分数[J].实用放射学杂志，2018，34（6）：959-961.
[10]	龚艳君，易铁慈，杨帆，等.基于冠状动脉CT 血管造影的血流储备分数评价心肌缺血的价值[J].中国介入心脏病学杂志，2019，27（12）：673-678.
[11]	靳文剑.冠状动脉CT 血管造影在冠状动脉起源变异中的应用[J].中国药物与临床，2019，19（7）：118-119.
[12]	耿文磊，胡奉环，尹栋，等.CT 血流储备分数对心肌缺血病变的诊断效能[J].中国医学影像技术，2020，36（2）：171-176.
[13]	熊青峰，马小静，陈艳，等.冠脉CTA 心肌血流指数诊断钙化斑块相关冠心病的临床意义[J].放射学实践，2019，34（12）：1327-1331.
[14]	武瑞凤.冠状动脉CT 血管成像联合动态心电图对冠心病心肌缺血的诊断价值[J].中国药物与临床，2020，20（7）：1094-1095.
[15]	徐永平，赵新斌，赵鹤亮.心肌桥-壁冠状动脉与心肌缺血的相关性研究[J].临床心血管病杂志，2018，34（7）：709-712.
[16]	王艺静，孙艳秋.CT 冠状动脉造影与心肌灌注的研究进展[J].新医学，2018，49（9）：624-627.
[17]	周文辉，熊志，柯岩，等.基于冠状动脉CTA 定量计算与心肌缺血临床表现的相关性分析[J].中国CT 和MRI 杂志，2018，16（10）：49-51.
[18]	单冬凯，杨俊杰，窦冠华，等.冠状动脉CT 血管造影获得的无创血流储备分数对心肌缺血的诊断价值[J].解放军医学杂志，2018，43（1）：33-37.