经皮肾镜碎石术后患者血清降钙素原、C反应蛋白水平变化对全身炎症反应综合征早期诊断的临床意义

Abstract
Figure/Table
References (18)
Related Citation (15)

Download: PDF (621 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the clinical significance of changes in serum procalcitonin (PCT) and C-reactive protein (CRP) levels in the early diagnosis of systemic inflammatory response syndrome (SIRS) in patients after percutaneous nephrolithotomy. Methods A total of 40 patients with SIRS after percutaneous nephrolithotomy in Xinyu People′s Hospital from February 2018 to February 2020 were retrospectively selected as the observation group, and 40 patients who had not undergone percutaneous nephrolithotomy during the same period were selected as the control group. The data of patients with SIRS were included in the control group. All patients were tested for serum PCT and CRP levels at 24 h before surgery, 2 h after surgery and 24 h after surgery. Serum PCT and CRP levels were compared between the two groups, the value of serum PCT and CRP levels in the early diagnosis of SIRS after percutaneous nephrolithotomy were analyzed. Results Twenty four hours after operation, the serum PCT and CRP levels of the two groups were higher than those at 24 h before operation and 2 h after operation, the serum PCT and CRP levels of the two groups at 2 h after operation were higher than those at 24 h before operation, the serum PCT and CRP levels in the observation group at 2 and 24 h after operation were higher than those in the control group, and the differences were statistically significant (P＜0.05). The area under the curve values of serum PCT and CRP levels and combined detection were 0.849, 0.826, 0.861, respectively. Conclusion The detection of serum PCT and CRP levels has a high application value in the early diagnosis of SIRS in patients after percutaneous nephrolithotomy, the higher the serum PCT and CRP levels, the greater the risk of SIRS after surgery.

Key words： Percutaneous nephrolithotomy Systemic inflammatory response syndrome Procalcitonin C-reactive protein Early diagnosis

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I13/77

[1]	李铁，薛超，及东林，等.经皮肾镜碎石术和输尿管软镜碎石术治疗肾结石的临床疗效比较和对机体氧化应激状态的影响[J].国际泌尿系统杂志，2017，37（3）：361-364.
[2]	徐辉，谢天朋，肖日海，等.小剂量地塞米松预防经皮肾镜取石术并发全身炎症反应综合征的疗效观察[J].微创泌尿外科杂志，2018，7（6）：389-392.
[3]	杨辉，罗倩，陈君灏，等.血清PCT、CRP 及内毒素在细菌性血流感染所致脓毒症患者中的早期诊断价值[J].现代生物医学进展，2017，17（2）：338-341.
[4]	王绍鸣，张才明.细菌性血流感染致脓毒症患者血清PCT、CRP 及内毒素水平变化及临床意义[J].解放军医药杂志，2018，30（1）：53-55，63.
[5]	那彦群，叶章群，孙颖浩，等.中国泌尿外科疾病诊断治疗指南手册：2014 版[M].北京：人民卫生出版社，2014：296-297.
[6]	张斌，韦海宗，常德辉.输尿管软镜与微通道经皮肾镜碎石术治疗肾盏结石的疗效比较[J].西北国防医学杂志，2018，39（9）：570-573.
[7]	刘军，何炜，项立波，等.直径2～3 cm 肾结石患者经输尿管软镜钬激光碎石术与经皮肾镜取石术的临床效果比较[J].广西医科大学学报，2020，37（3）：501-506.
[8]	史建国，王卫宁，王领军，等.中性粒细胞/淋巴细胞比值——预测上尿路结石经皮肾镜术后全身炎症反应综合征的新指标[J].河北医科大学学报，2018，39（12）：1398-1401.
[9]	孙景巍，彭万胜，黄玉柱，等.小儿肺炎支原体肺炎合并全身炎症反应综合征时超敏CRP，PCT，WBC 变化及临床意义研究[J].中华全科医学，2019，17（2）：245-247，255.
[10]	王冠，郑美娜，秦少游，等.不同严重程度急性胰腺炎患者血清中PCT，hs-CRP，TNF-α 水平及临床意义[J].现代生物医学进展，2019，19（14）：2699-2702，2711.
[11]	刘雅静.降钙素原、C 反应蛋白和肿瘤坏死因子-α 在儿童全身炎症反应综合征早期诊断中的应用[J].实用临床医药杂志，2019，23（1）：103-105.
[12]	江庆斌，李东松，洪文光，等.PCT，CRP 及WBC 计数在诊断胆石症合并胆道感染及SIRS 中的临床应用价值[J].中国普外基础与临床杂志，2020，27（8）：945-949.
[13]	胡杨，刘春峰.SIRS 标准及C-反应蛋白对儿科急诊发热患儿重症感染情况的判定及预测作用[J].中国小儿急救医学，2017，24（7）：517-522.
[14]	廖宴，戴娟，黄文龙，等.不同分级及转归脓毒症患者血清PCT，D-D，CRP 及血小板相关参数检测的临床意义[J].现代生物医学进展，2020，20（18）：3453-3456，3452.
[15]	王婷，韦小碗，杨亮，等.脓毒症患者血清PCT，CRP，IL-6和IL-10 水平检测及临床意义[J].陕西医学杂志，2020，49（11）：144-148.
[16]	陈钢，黄明伟，孔来法，等.创伤外科感染患者与全身炎症反应综合征评分及血清学指标相关性研究[J].中国预防医学杂志，2019，20（8）：686-690.
[17]	荆梦君.PCT、IL-6、D-D 水平与脓毒症严重程度和预后的相关性分析[J].中外医学研究，2022，20（3）：66-70.
[18]	程洁，陈新.血清D-二聚体、降钙素原水平对采用连续肾脏替代疗法治疗的脓毒症伴急性肾损伤患者预后的预测价值分析[J].中国当代医药，2021，28（30）：64-67.