脑电双频指数联合躁动-镇静评分在机械通气患者镇静评价中的应用效果

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Abstract Objective To investigate the application effect of bispectral index (BIS) combined with Richmond agitationsedation scale (RASS) in the sedation evaluation of patients with mechanical ventilation. Methods A total of 60 patients with mechanical ventilation in the Emergency Intensive Care Unit (EICU) of Nanchang First Hospital from December 2019 to June 2020 were divided into control group (n=30) and experimental group (n=30) by the random number table method. The control group was treated only with routine sedation therapy, and the experimental group was treated with BIS combined with RASS score to guide sedation therapy. The treatment time of EICU, the total use of sedatives, the time of mechanical ventilation, the adverse reactions during the diagnosis and treatment of EICU and the total hospital stay were compared between the two groups. Results The duration of EICU stay and mechanical ventilation in experimental group was shorter than that in control group, and the total incidence of adverse events was lower than that in control group, with statistical significances (P<0.05). There was no significant difference in total hospital stay between the two groups (P>0.05). The total amount of Midazolam in experimental group was less than that in control group, the difference was statistically significant (P<0.05). There was no significant difference in the total amount of dexmedetomidine between the two groups (P>0.05). Conclusion Sedation therapy guided by RASS score combined with BIS can significantly shorten the time of mechanical ventilation, the time of EICU treatment, reduce the dose of sedatives and the total incidence of adverse events, which is worthy of clinical promotion.

Key words： Sedation score Mechanical ventilation Sedation assessment Bispectral index Richmond agitation-sedation score

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