脊柱椎体间植入物材料优化的研究进展

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Abstract

The application of interbody implants in spinal surgery can promote the fusion between vertebral bodies of spine. In recent years, with the increase of the number of spinal fusion operations, a large number of studies have been devoted to optimizing the mechanical and biological characteristics of interbody implants to promote bone fusion. The earliest used interbody implant was made of autologous cortical bone. At present, titanium alloy and polyether ether ketone (PEEK) are the two most widely used and common materials in application and research. Although the elastic modulus of titanium is much higher than that of natural bone, its bone integration performance is better than PEEK.The elastic modulus of PEEK is close to that of bone, but it does not have some excellent biological properties of titanium. Increasing the porosity and surface roughness of titanium implants can improve the mechanical properties of titanium implants, while the biological properties of PEEK can be enhanced by surface coating technology using titanium or hydroxyapatite. Using additive manufacturing technology and some metals with antibacterial activity can improve the material properties from another point of view, so as to further improve the performance of implants. This review focuses on the recent research progress of titanium alloy and PEEK implant material modification and surface treatment technology, aiming to provide reference for improving the fusion rate of spine surgery.

Key words： Implants Titanium Polyether ether ketone Porosity Coating

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