内科胸腔镜联合不同方案治疗结核性包裹性胸腔积液的效果

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Abstract Objective To evaluate the therapeutic effect and safety of three different treatment schemes of medical thoracoscopy, medical thoracoscopy combined with microcapsule vaccine and medical thoracoscopy combined with cryotherapy in the treatment of tuberculous encapsulated pleural and peritoneal effusion, so as to find out the best clinical treatment scheme. Methods A total of 60 patients with tuberculous encapsulated pleural and peritoneal effusion treated in Yichun People′s Hospital from January 2019 to December 2020 were selected as the research objects. They were divided into group X (20 cases), group W (20 cases) and group L (20 cases) according to random number table method. Group X used the medical thoracoscopy, group W used medical thoracoscopy combined with microcapsule vaccine, and group L used medical thoracoscopy combined with cryotherapy. The disappearance time of clinical symptoms,normal temperature, days of catheterization, the total amount of pleural fluid, the score of pleural encapsulation range,interleukine-2 (IL-27) value, CD3+ value and CD8+ value among the three groups were compared. Results The disappearance time of clinical symptoms, the normal time of normal temperature and the days of catheterization in group L were shorter than those in group X, group W, the total amount of pleural fluid in group L were less than those in group X and group W, the score of pleural encapsulation range in group L were lower than those in group X and group W, the level of IL-27 in group L were lower than those in group X and group W, and the levels of CD3+ and CD8+ in group L were higher than those in group X and group W, the differences were statistically significant (P＜0.05). The disappearance time of clinical symptoms, the normal time of body temperature and the days of catheterization in group X were shorter than those in group W, the total amount of pleural effusion in group X was less than that in group W, the score of pleural encapsulation range in group X was lower than that in group W, the level of IL-27 in group X was lower than that in group W, and the levels of CD3+ and CD8+ in group X were higher than those in group W, the differences were statistically significant (P＜0.05). Conclusion The effect of medical thoracoscopy combined with cryotherapy in the treatment of tuberculous encapsulated pleural and peritoneal effusion is better, which is worthy of further clinical promotion.

Key words： Medical thoracoscope Microcapsule vaccine Cryotherapy Tuberculous encapsulated pleural and peritoneal effusion

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