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| Effect of Wuling Powder and Danggui Buxue Decoction in treating swelling of limbs with fractures |
| WANG Daguang |
| Department of Orthopedics,Caidian District Hospital of Traditional Chinese Medicine |
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Abstract Objective To investigate the effect of Wuling Powder and Danggui Buxue Decoction in the treatment of swelling of limbs.Methods A total of 150 patients with fractured limbs and swelling who were treated at the Caidian District Hospital of Traditional Chinese Medicine in Wuhan City from December 2019 to January 2021 were selected as the research objects,according to the random number table method,they were divided into control group (75 cases) and observation group (75 cases).The control group was given routine treatment.The observation group was treated with Wuling Powder and Danggui Buxue Decoction.The clinical symptom scores of the two groups were compared before and after treatment (visual analogue scale[VAS],limb swelling degree,adjacent joint range of motion score),bone metabolism index level (osteocalcin[BGP],serum alkaline phosphatase[ALP],type I procollagen carboxy-terminal peptide[PICP]and bone morphogenetic protein-2[BMP-2]),bone callus Growth condition[callus density,callus volume,callus edge,growth condition of stump edge]and clinical efficacy.Results Before treatment,there was no significant difference in the VAS score,the degree of swelling of limbs and the range of motion of adjacent joints between the two groups (P＞0.05).The scores were lower than those before treatment in this group,and the differences were statistically significant (P＜0.05).After treatment,the VAS score,the degree of swelling of the limbs and the range of motion of adjacent joints in the observation group were lower than those in the control group,and the differences were statistically significant (P＜0.05).Before treatment,there was no significant difference in the levels of BGP,ALP,PICP and BMP-2 between the two groups (P＞0.05).After treatment,the levels of BGP,ALP,PICP and BMP-2 in the two groups were higher than before treatment,the differences were statistically significant in this group (P＜0.05).After treatment,the levels of BGP,ALP,PICP and BMP-2 in the observation group were higher than those in the control group,and the differences were statistically significant (P＜0.05).Before treatment,there was no significant difference in the callus density,callus volume,callus edge and fracture edge growth score between the two groups (P＞0.05).The volume,callus edge,and fracture edge growth scores of the patients in the observation group were higher than those before treatment,and the differences were statistically significant (P＜0.05).The end-edge growth scores were higher than those in the control group,and the differences were statistically significant (P＜0.05).The total effective rate of clinical treatment in the observation group was 93.33% (70/75) higher than that in the control group,which was 81.33% (61/75),and the difference was statistically significant (P＜0.05).Conclusion The treatment of Wulingsan combined with Danggui Buxue Decoction for patients with swelling of fractured limbs can effectively reduce the symptoms of swelling and pain,improve the level of bone metabolism and promote the growth of callus,which is beneficial to fracture healing.
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