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| Effect of mitral annuloplasty in the treatment of mitral regurgitation caused by left ventricle enlargement |
| LI Xu-dong HU Ning-dong LIU Qiu-hua LIANG Ji-huan WAN Hai-xia XIA Xu |
| Department of Cardiothoracic Surgery, Qingyuan People′s Hospital, Guangdong Province, Qingyuan 511500, China |
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Abstract Objective To explore the effect of mitral annuloplasty in the treatment of mitral regurgitation caused by left ventricle enlargement. Methods Forty patients with mitral regurgitation caused by left ventricle enlargement treated in cardiothoracic surgery department of our hospital from January 2013 to June 2019 were selected as the research objects and divided into two groups by the random number method. Mitral valve replacement was performed in patients in the control group (n=20), and mitral annuloplasty was performed in patients in the observation group (n=20). The operation curative effect, operation indexes and heart function (left ventricular end-diastolic diameter [LVEDD], left ventricular end-systolic diameter [LVESD], left ventricular ejection fraction [LVEF], the left atrial diameter [LAD] and cardiac function grading) before and after operation were compared between the two groups. Results There were no statistically significant differences in the operative successful rate, the reoperation rate, the incidence rate of complications and the intraoperative or postoperative mortality between the two groups (P＞0.05). The blocking time and the cardiopulmonary bypass time in the observation group were longer than those in the control group, with statistically significant differences (P＜0.05). There were no statistically significant differences in the drainage volume 1 day after the operation and the length of hospital stay between the two groups (P＞0.05). There were no statistically significant differences in the LVEDD, LVESD, LVEF, LAD, cardiac function grading before operation and 6 months after the operation between the observation group and the control group (P＞0.05). In the two groups, LVEDD, LVESD, LAD at 6 months after the operation were smaller than those before operation, the cardiac function grading at 6 months after the operation was lower than that before operation, and LVEF at 6 months after the operation was higher than that before operation, with statistically significant differences (P＜0.05). Conclusion The effect of mitral annuloplasty in the treatment of mitral regurgitation caused by left ventricle enlargement is significant, with high operative successful rate and low incidence rate of complications. It is also able to effectively improve the heart function, correct valve regurgitation, and avoid the long-term anticoagulant treatment needed by the replacement, which has positive clinical significance.
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| [2] |
黄健兵，丁芳宝，张韫佼，等.动脉导管未闭合并功能性二尖瓣返流的治疗策略[J].中国心血管病研究，2016，14（12）：1119-1122.
|
| [3] |
刘盛，仲肇基，孙寒松，等.二尖瓣成形和置换术治疗室壁瘤合并缺血性二尖瓣返流的对比研究[J].中国循证心血管医学杂志，2017，9（2）：164-167.
|
| [4] |
潘砚鹏，陈红卫，陈文宽，等.二尖瓣成形与置换术治疗重度缺血性二尖瓣反流近中期疗效比较[J].心肺血管病杂志，2019，38（10）：1032-1035.
|
| [5] |
熊峰，冯坤，王淑珍，等.二尖瓣成形术在二尖瓣反流治疗中的疗效评价[J].岭南心血管病杂志，2016，22（5）：569-572.
|
| [6] |
潘砚鹏，陈红卫，蒋艳艳，等.“缘对缘”联合人工瓣环修复术治疗二尖瓣关闭不全42 例分析[J].中国心血管病研究，2015，13（10）：948-951.
|
| [7] |
盛亚运.二尖瓣成形与置换术在二尖瓣反流性疾病中临床疗效的对比研究[D].芜湖：皖南医学院，2018：1-59.
|
| [8] |
邱志兵，邵俊杰，秦卫，等.二尖瓣修复术与置换术在重度缺血性二尖瓣反流中的疗效比较[J].中华医学杂志，2017，97（22）：1705-1709.
|
| [9] |
Mihos CG,Santana O.Is an adjunctive subvalvular repair during mitral annuloplasty for secondary mitral regurgitation effective in preventing recurrent regurgitation?[J].Interact Cardiovasc Thorac Surg, 2016，22（2）：216-221.
|
| [10] |
韩劲松，尹宗涛，王辉山，等.Carpentier-Edwards 生理环在退行性二尖瓣关闭不全二尖瓣成形术中的应用[J].中国心血管病研究，2015，13（5）：464-466，476.
|
| [11] |
肖琳，黄信生.不停跳搭桥联合新型二尖瓣成形术治疗轻-中度缺血性二尖瓣反流患者的临床研究[J].中国医药导刊，2019，21（5）：273-277.
|
| [12] |
白杨.12 例二尖瓣成形术治疗二尖瓣关闭不全的临床研究[D].石家庄：河北医科大学，2018：1-55.
|
| [13] |
栾果，安永.二尖瓣成形术治疗儿童二尖瓣关闭不全的研究进展[J].重庆医学，2019，48（12）：2099-2101，2106.
|
| [14] |
刘鑫荣，胡仁杰，孙彦隽，等.人工二尖瓣瓣环治疗小儿二尖瓣反流疗效及近期随访[J].中华胸心血管外科杂志，2019，35（7）：402-405.
|
| [15] |
刘江波，罗鸿，付庆林，等.二尖瓣成形术和置换术治疗重度缺血性二尖瓣关闭不全的效果比较[J].河南医学研究，2018，27（24）：4426-4429.
|
| [1] |
刘若凡，许建屏.成形还是换瓣？ 二尖瓣返流治疗手术策略再探讨[J].中国心血管病研究，2016，14（7）：585-587.
|
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