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| Clinical observation of Huoxue Qingre Jiedu method in the treatment of diabetic foot |
| WANG Zhixiang QIU Zucai DU Lanxiang LIU Shengfei LI Shijia |
| Department of Orthopedics, Ganzhou Hospital of Traditional Chinese Medicine, Jiangxi Province, Ganzhou 341000,China |
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Abstract Objective To analyze the clinical effect of Huoxue Qingre Jiedu method in the treatment of diabetic foot.Methods A total of 50 patients with diabetic foot admitted in Ganzhou Hospital of Traditional Chinese Medicine in Jiangxi Province from September 2020 to October 2021 were selected as subjects. They were divided into control group and observation group by random number table method, with 25 cases in each group. The control group received basic treatment, and the observation group received basic treatment and Huoxue Qingre Jiedu method. The treatment efficiency, ulcer area, blood flow velocity of dorsalis pedis artery, hemorheology and inflammatory factor levels were compared between the two groups. Results The effective rate of observation group was 96.00%, which was higher than that of control group (64.00%) (P＜0.05). There were no significant differences in ulcer area and blood flow velocity of dorsal foot artery between the two groups before treatment (P＞0.05). After treatment, the ulcer area in observation group was smaller than that in control group, and the blood flow velocity of dorsal foot artery was higher than that in control group(P＜0.05). There were no significant differences in whole blood viscosity (hypercut), plasma viscosity, fibrinogen and glycosylated hemoglobin levels between the two groups before treatment (P＞0.05). After treatment, whole blood viscosity(hypercut), plasma viscosity and fibrinogen levels in observation group were lower than those in control group (P＜0.05).There was no significant difference in glycosylated hemoglobin level between the two groups after treatment (P＞0.05).There were no significant differences in the levels of C-reactive protein (CRP), procalcitonin (PCT) and D-dimer (D-D)between the two groups before treatment (P＞0.05). The CRP, PCT and D-D levels in observation group were lower than those in control group after treatment (P＜0.05). Conclusion The effect of Huoxue Qingre Jiedu method in the auxiliary treatment of diabetic foot is good, which can reduce the degree of wound infection, accelerate healing, improve blood rheology and reduce blood viscosity, which is worthy of clinical application and promotion.
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