高流量氧疗与无创机械通气在术后轻中度低氧血症患者中的应用效果

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Abstract Objective To investigate the effect of high flow oxygen therapy and non-invasive mechanical ventilation on patients with mild to moderate hypoxemia during postoperative evacuation. Methods A retrospective study of 732 adult patients with mild to moderate hypoxemia during postoperative ICU withdrawal from 2008 to 2019 was included in the Medical Information Mark for Intensive Care Ⅳ. By matching propensity score, they were divided into high-flow group(213 cases) and non-invasive ventilation group (213 cases) according to treatment mode after discontinuation of the machine. Baseline data, 48 h reintubation rate, 28 d reintubation rate, 28 d mortality, time from disengagement to reintubation, length of hospital stay and length of stay in ICU were compared between the two groups. The above indexes of moderate hypoxemia patients in the two groups were separately analyzed after discontinuation of the machine, and 73 cases in each group were included through matching propensity score. Results In patients with mild to moderate hypoxemia, there was no significant difference in the 48 h reintubation rate, 28 d reintubation rate and 28 d mortality between the two groups (P>0.05). The hospitalization time, ICU stay time and intubation time after extubation in the highflow group were longer than those in the non-invasive ventilation group, the differences were statistically significant (P<0.05). In moderate hypoxemia, there were no significant differences in 48 h reintubation rate, 28 d reintubation rate, 28 d mortality, time from discontinuation to reintubation, length of hospital stay and length of ICU stay between the two groups (P>0.05). Conclusion For patients with mild to moderate hypoxemia when weaning from ventilator, the main efficacy indicators of high-flow oxygen therapy were similar to those of non-invasive mechanical ventilation, but hospital stay and ICU stay were shorter in patients with non-invasive mechanical ventilation.

Key words： High-flow oxygen therapy Surgery Hypoxemia Non-invasive mechanical ventilation Medical Information Mart for Intensive Care

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	SU Lingling
	XU Chunmei
	ZHANG Aiping
	LI Weichun

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SU Lingling,XU Chunmei,ZHANG Aiping, et al. Application effect of high-flow oxygen therapy and non-invasive mechanical ventilation in patients with mild to moderate hypoxemia after surgery[J]. 中国当代医药, 2022, 29(6): 15-19.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I6/15

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