翼状胬肉切除联合角膜缘干细胞移植术治疗翼状胬肉的临床效果

Abstract
Figure/Table
References (19)
Related Citation (15)

Download: PDF (420 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the clinical effect of pterygium resection combined with limbal stem cell transplantation in the treatment of pterygium. Methods The clinical data of 238 patients with pterygium who were treated in the Department of Ophthalmology of Jianli Third People′s Hospital from July 2015 to December 2019 were selected for retrospective analysis. According to different surgical methods, they were divided into observation groups (n=119, 141 eyes)and the control group (n=119, 140 eyes). The control group used triamcinolone acetonide marked pterygium resection combined with pedicled conjunctival flap transfer, and the observation group pterygium resection combined with limbal stem cell transplantation, the clinical efficacy, total complication incidence, recurrence rate, epithelial repair time and hospitalization time of the two groups were compared, and the postoperative naked eye vision and corneal astigmatism of the two groups were compared. Results The total effective rate of treatment in the observation group was higher than that in the control group, the difference was significant (P＜0.05). The hospitalization time, corneal epithelial repair time, and recurrence rate of the observation group were lower than those of the control group, the differences were significant (P＜0.05). There was no statistically significant difference between the two groups in the incidence of complications, corneal astigmatism and uncorrected visual acuity one month after surgery (P＞0.05). Conclusion Limbal stem cell transplantation can improve the therapeutic effect of patients with pterygium, and has positive significance in reducing the recurrence rate after surgery and shortening the recovery time of the disease.

Key words： Pterygium Limbal stem cell transplantation Pterygium Clinical effect

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHOU Dayan

Cite this article:

ZHOU Dayan. Clinical effect of pterygium resection combined with corneal limbal stem cell transplantation in the treatment of pterygium[J]. 中国当代医药, 2022, 29(2): 123-126.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2022/V29/I2/123

[1]	孙莉，李霞.翼状胬肉流行病学及发病机制研究进展[J].广西医科大学学报，2017，34（1）：132-135.
[2]	张风莉，王玉琴.翼状胬肉手术后发生的肉芽肿临床与病理学分析[J].中华眼外伤职业眼病杂志，2019，41（10）：793-795.
[3]	于静，向其元.手术切除联合自体血清滴眼液治疗翼状胬肉的疗效观察[J].国际眼科杂志，2017，17（4）：713-715.
[4]	李凤鸣.中华眼科学[M].北京：人民卫生出版社，2005.
[5]	李珊，裴蓓，孙阿利，等.手术切除联合角膜缘干细胞移植治疗翼状胬肉的效果及对泪膜和视觉功能的影响[J].中国医药导报，2021，18（12）：138-141.
[6]	沈韵之，许咪，孙松.原发性与复发性翼状胬肉的临床指标及实验室指标差异[J].国际眼科杂志，2020，20（4）：639-642.
[7]	邢懿，江方方，姜波，等.合肥地区116 例老年患者翼状胬肉流行病学表现及危险因素分析[J].中华全科医学，2020，18（8）：1279-1282.
[8]	张俊芳，杨梅，朱蓉嵘，等.江苏省阜宁县农村50 岁及以上人群翼状胬肉流行病学调查及相关危险因素分析[J].中华实验眼科杂志，2019，37（3）：212-217.
[9]	张云青.翼状胬肉与干眼的相关性研究[J].基层医学论坛，2020，24（32）：4606-4608.
[10]	杜莲娟.单纯翼状胬肉切除术与翼状胬肉切除术结膜移植术术后效果及复发率对比[J].世界最新医学信息文摘（连续型电子期刊），2021，21（20）：126-127.
[11]	姚帮桃，丁宇华，赵孝贵，等.下方不同宽窄自体角膜缘移植瓣治疗翼状胬肉对术后眼表泪膜的影响[J].中国眼耳鼻喉科杂志，2021，21（3）：208-211.
[12]	李正义，华峰，陈宝伟.新型非甾体滴眼液对减轻翼状胬肉术后疼痛的效果观察[J].中国医师进修杂志，2020，43（6）：545-548.
[13]	高娟玉，顾宇亮，黄学东.双氯芬酸钠滴眼液和玻璃酸钠滴眼液联合治疗复发性翼状胬肉术后干眼症的临床效果[J].临床医学研究与实践，2019，4（4）：85-86.
[14]	王金华，伍志琴，苏凡凡，等.带角膜缘的自体结膜瓣移植术治疗翼状胬肉合并结膜囊肿[J].国际眼科杂志，2017，17（6）：1143-1146.
[15]	刘剑锐.自体角膜缘干细胞移植术联合翼状胬肉切除术对翼状胬肉患者泪膜功能的影响[J].基层医学论坛，2021，25（8）：1180-1181.
[16]	谢世华，廖伍全，魏馥贤.翼状胬肉切除和自体角膜缘干细胞移植对创面上修复及创面愈合时间的影响分析[J].当代医学，2018，24（26）：130-131.
[17]	富强.角膜缘干细胞移植联合MMC 在翼状胬肉手术中的应用[Z].齐齐哈尔医学院第一附属医院，2014.
[18]	徐夏冰，杜波.角膜缘干细胞移植术后应用玻璃酸钠滴眼液对翼状胬肉复发率及眼表症状的影响[J].临床医学研究与实践，2021，6（12）：107-109.
[19]	雷新建.翼状胬肉切除联合角膜缘干细胞移植术与单纯翼状胬肉切除术对翼状胬肉患者治愈与复发及术后恢复的影响观察[J].贵州医药，2020，44（4）：613-615.