2型糖尿病患者并发糖尿病肾病微量白蛋白尿的影响因素研究

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Abstract Objective To explore the influencing factors of type 2 diabetes mellitus (T2DM) complicated with diabetic kidney disease (DKD) microalbuminuria. Methods A total of 308 T2DM patients from two tertiary A hospitals in Hengyang City from August 2020 to April 2021 as the research objects. Patients were divided into groups according to the occurrence of microalbuminuria, urinary albumin excretion rate (UAER) of 30-300 mg/24 h was included in the DKD group, UAER＜30 mg/24 h was included in the non-DKD group. The influencing factors of DKD in T2DM patients were analyzed by binary logistic regression. Results Among 308 T2DM patients in this study, 136 (44.16%) were DKD microalbuminuria patients and 172 (55.84%) were non-DKD microalbuminuria patients. Univariate analysis showed that age, duration of diabetes, systolic blood pressure, diastolic blood pressure, low density lipoprotein cholesterol (LDL-C),fasting blood glucose (FPG), glycosylated hemoglobin (HbA1c), proportion of history of hypertension and proportion of abdominal obesity in DKD group were higher than those in non-DKD group, self-efficacy score and health promotion lifestyle score in DKD group were lower than those of non-DKD group, and the differences were statistically significant(P＜0.05). The results of binary logistic regression analysis showed that the course of diabetes mellitus (β=0.055, OR=1.057, 95%CI=1.007-1.109), systolic blood pressure (β=0.039, OR=1.040, 95%CI=1.016-1.064), LDL-C (β=0.333,OR=1.395, 95%CI=1.017-1.914), abdominal obesity(β=0.596, OR=1.815, 95%CI=1.039-3.171), HbA1c(β=0.182, OR=1.199, 95%CI=1.071-1.344) were risk factors for DKD microalbuminuria in T2DM patients (P＜0.05), health promotion lifestyle score (β=-0.018, OR=0.983, 95%CI=0.967-0.998), self-efficacy score (β=-0.029, OR=0.972, 95%CI=0.948-0.996) was protective factors for DKD microalbuminuria in T2DM patients (P＜0.05). Conclusion With the prolonged duration of the course of diabetes mellitus and poor glycaemic control, T2DM patients are prone to kidney disease. Nurses should pay attention to improving the self-efficacy of the patients, advocating a health-promoting lifestyle, which can help prevent or delay the occurrence of microalbuminuria of diabetic kidney disease.

Key words： Type 2 diabetes mellitus Diabetic kidney disease Microalbuminuria Self-efficacy Health-promoting lifestyle Analysis of influencing factors

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	Articles by authors
	CHU Dongmei
	GUO Jiayu
	XIAO Luwei
	LENG Juanjuan
	LI Jianzhi▲

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CHU Dongmei,GUO Jiayu,XIAO Luwei, et al. Study on the influencing factors of type 2 diabetic complicated with diabetic kidney disease microalbuminuria[J]. 中国当代医药, 2022, 29(2): 55-59转64.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2022/V29/I2/55

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