Objective To investigate the influence of laryngeal mask airway and tracheal intubation on flatulence and postoperative nause and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy.Methods A total of 90 patients undergoing elective laparoscopic cholecystectomy at Changzhou Traditional Chinese Medicine Hospital from September 2016 to September 2017 were enrolled.According to the random number table methods, they were divided into the tracheal intubation (T) group, the laryngeal mask pressure control ventilation (P) group and the laryngeal mask volume control ventilation (V) group, 30 cases in each group.Ultrasound was used to measure changes in gastric antrum area (GAA) after successful placement of the laryngeal mask or tracheal tube (T0) and after surgery (T1), and the incidence of PONV were compared between the three groups.Results There were no significant differences in GAA between the three groups at T0 (P＞0.05).The GAA of group V and group P at T1 were larger than those at T0, the differences were statistically significant (P＜0.05).The GAA at T1 of group V and group P were larger than those of group T,the differences were statistically significant (P＜0.05).The incidence of PONV of group V and group P were higher than that of group T, and the differences were statistically significant (P＜0.05).Conclusion Compared with conventional tracheal intubation, the degree of gastric distention and the incidence of PONV after general anesthesia with LMA are significantly increased.